Trending archive
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542 articles
March 202611
Combined resistance exercise and essential amino acid intake enhance follistatin/myostatin ratio and muscle fitness in older women: a randomized controlled trial.
This 12-week randomized controlled trial compared resistance exercise (RE), essential amino acid (EAA) supplementation, their combination, and control in 96 healthy women aged 65 years or older without insulin…
It's never too late: The impact of resistance training on strength and body composition in females across the lifespan - A systematic review and meta-analysis.
This systematic review and meta-analysis pooled 126 studies involving 4019 healthy women aged 18 years or older to assess resistance training effects on strength and body composition across the lifespan.
A Cluster-Randomized Clinical Trial of Silver Diamine Fluoride vs Atraumatic Restoration in Older Adults.
This multicenter cluster-randomized noninferiority trial compared biannual 38% silver diamine fluoride (SDF) with atraumatic restorative treatment (ART) plus fluoride varnish in adults aged 62 years or older living in…
Sarcopenia and Risk of Cardiovascular Events and Mortality: A Meta-analysis of Longitudinal Observational Studies.
This meta-analysis pooled longitudinal observational studies examining sarcopenia and related muscle traits in relation to cardiovascular outcomes.
Effect of Narrative-Based Palliative Care on Psychological Stress, Quality of Life, and End-of-Life Acceptance in Elderly Terminal Cancer Patients and Their Families.
This single-center randomized controlled study evaluated narrative-based palliative care in 50 elderly patients with terminal cancer and their family caregivers.
Process evaluation results of FEMuR III randomised controlled trial (RCT), a community-based rehabilitation following hip fracture surgery.
This mixed-methods process evaluation examined implementation of FEMuR, a community-based rehabilitation programme after hip fracture surgery, delivered across 13 sites within a randomised controlled trial.
Effect of assistive technology on the burden of caregivers to older adults: A systematic review.
This systematic review without meta-analysis examined whether assistive technologies reduce caregiving burden for older adults with cognitive impairments or disabilities.
Efficacy of Progressive Exercise Snacking for Middle-Aged and Older Adults With Knee Osteoarthritis: A Systematic Review and Meta-analysis.
This systematic review and meta-analysis assessed progressive exercise snacking (PES) for middle-aged and older adults with knee osteoarthritis. It included 18 randomized controlled trials involving 1,200 participants.
Preserving identity through caregiving: A systematic review and meta-synthesis of minority informal caregivers' experiences caring for older adults with neurological conditions.
This systematic review and thematic meta-synthesis examined how ethnic minority informal caregivers in Europe understand and navigate caring for older adults with neurological conditions.
A first-in-human Phase 1/1b randomized trial evaluating the safety and immunogenicity of a respiratory syncytial virus (RSV) virus-like particle subunit vaccine (IVX-121) in healthy young and older adults.
This randomized Phase 1/1b trial evaluated the safety and immunogenicity of IVX-121, an investigational RSV virus-like particle vaccine, in 90 healthy adults aged 18–45 years and 130 aged 60–75 years.
Therapeutic effects of Xianlinggubao capsules on knee function, inflammatory response, and bone metabolism in elderly patients with degenerative knee osteoarthritis.
This randomised controlled trial evaluated Xianlinggubao (XLGB) capsules added to celecoxib in 100 elderly patients with degenerative knee osteoarthritis.
February 20267
Views and Experiences of People With Dementia, Informal Caregivers and Professionals on Eating and Drinking Difficulties: A Qualitative Systematic Review.
This qualitative systematic review examined how people with dementia, informal caregivers and professionals experience eating and drinking difficulties.
Standards for Hospital Falls Prevention and Management: An International Comparative Analysis.
This international comparative analysis examined the content and quality of hospital standards addressing falls. Researchers searched databases, grey literature, and organisational websites for standards used across…
Mechanical thrombectomy for elderly stroke patients: An updated systematic review and meta-analysis of randomized clinical trials.
This systematic review and meta-analysis pooled randomized clinical trials comparing mechanical thrombectomy (MT) with standard medical management for acute ischemic stroke in patients over 70 years.
Models of Care and Interventions to Improve Person-Centred Care for Older People in Long-Term Care Facilities: A Mixed Methods Systematic Review.
This mixed methods systematic review examined care models and interventions intended to improve person-centred care for older people in long-term care facilities.
Comparison of opioid-free versus opioid-based total intravenous anaesthesia in elderly patients undergoing short-duration surgery: a randomized controlled trial.
This single-centre randomized controlled trial in China compared opioid-free total intravenous anaesthesia (OFA) with opioid-based total intravenous anaesthesia (OBA) in 400 patients aged 60 years or older undergoing…
Safety and Efficacy of Glucagon-Like Peptide-1 Receptor Agonists Use in Elderly People With Obesity-A Meta-Analysis.
This systematic review and meta-analysis compared GLP-1 receptor agonist safety and efficacy in adults aged 65 years or older with obesity versus younger adults, including people with or without type 2 diabetes.
Methods and Measures Utilized in Older Adult Physical Activity Intervention Assessments: A Systematic Review.
This systematic review examined how physical activity outcomes were assessed in interventions involving older adults. The authors reviewed 45 articles identified through PubMed, CINAHL, and PsycInfo, considering study…
January 20266
The effectiveness of psychological interventions for older adults with hip fractures: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated theory-based psychological interventions for psychosocial outcomes and physical function in older adults with hip fractures.
Prevalence and incidence of post-intensive care syndrome among intensive care unit survivors: a systematic review and meta-analysis.
This systematic review and random-effects meta-analysis examined post-intensive care syndrome (PICS) among intensive care unit survivors, synthesising 34 cross-sectional and cohort studies with 6230 participants.
Emerging Role of Portable Accelerometers for Assessment of Gait Instability in Idiopathic Normal Pressure Hydrocephalus: A Systematic Review.
This PRISMA-guided systematic review assessed portable and smartphone-based accelerometers for measuring gait in idiopathic normal pressure hydrocephalus (iNPH).
Heliox ventilation promotes pulmonary circulation and cardiac function in elderly hypertensive patients: a randomized controlled trial.
This randomized controlled study compared heliox with conventional nitrogen–oxygen ventilation in 40 elderly hypertensive patients requiring invasive mechanical ventilation in an intensive care unit.
Reperfusion therapy for older patients with acute myocardial infarction and cardiogenic shock.
This systematic review and meta-analysis assessed reperfusion therapy versus non-reperfusion care in patients aged ≥75 years with acute myocardial infarction (AMI) and cardiogenic shock (CS).
Tai Chi modulating multimodal connectivity patterns and cognitive function in cerebral small vessel disease.
This randomized controlled trial examined whether Tai Chi affects cognition and brain connectivity in 51 patients with cerebral small vessel disease (CSVD).
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