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2000 articles
November 202624
Progression-Associated Loss of SMARCB1/INI1 Expression in Mismatch Repair-Deficient Glioblastoma.
A patient with mismatch repair-deficient glioblastoma had a recurrent tumor in which testing identified a second SMARCB1 mutation and complete loss of SMARCB1/INI1 protein expression.
Effects of nutrition counseling on quality of life in adults with cancer: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed randomized controlled trials of nutrition counseling and quality of life (QoL) in adults with cancer.
Successful rechallenge with almonertinib and corticosteroids after gefitinib-induced interstitial lung disease: A case report and literature review.
A 53-year-old never-smoking woman with stage IV, EGFR L858R-mutant lung adenocarcinoma developed progressive dyspnea and hypoxemia after two months of gefitinib, despite an initial tumor response.
Pulmonary sarcomatoid carcinoma with METex14 mutation and high PD-L1: A case report.
A previously healthy 54-year-old man presented with persistent cough and diminished breath sounds over the right upper lung.
Comparative efficacy and safety of second- and later-line BRAF-targeted regimens in BRAF V600E-mutant metastatic colorectal cancer: A systematic review and network meta-analysis.
This systematic review and network meta-analysis compared the efficacy and safety of second- and later-line BRAF-targeted regimens in adults with BRAF V600E-mutant metastatic colorectal cancer.
Primary splenic angiosarcoma initially diagnosed as littoral cell angioma: A case report of a diagnostic pitfall.
A 71-year-old woman presented with left upper abdominal pain, severe anemia, thrombocytopenia, and a splenic lesion. After splenectomy, the lesion was initially diagnosed as littoral cell angioma; a separate hepatic…
Synchronous hepatocellular carcinoma and nasopharyngeal carcinoma in a patient with chronic hepatitis B: A case report and literature review.
A 63-year-old Chinese man with chronic hepatitis B was found on routine screening to have a liver mass and reported nasal obstruction.
Prognostic Value of the Preoperative Systemic Immune-Inflammation Index for Overall Survival After Surgical Resection for Gallbladder Cancer: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed whether preoperative systemic immune-inflammation index (SII) is associated with overall survival after gallbladder cancer resection.
Sequential therapy with anlotinib and radioiodine for distant metastatic differentiated thyroid cancer: a phase II clinical trial.
This prospective, single-arm phase II trial evaluated sequential anlotinib and radioiodine (RAI) in patients with measurable distant metastatic differentiated thyroid cancer (DTC).
Photobiomodulation for radiotherapy-induced dysgeusia in head and neck cancer patients: a pilot randomized clinical trial.
This pilot randomized clinical trial compared photobiomodulation (PBM) with zinc sulfate for radiotherapy-induced dysgeusia in 16 patients with head and neck cancer.
A phase 1 study of 4'-thio-2'-deoxycytidine in patients with solid tumors.
This phase 1 dose-escalation study evaluated oral 4′-thio-2′-deoxycytidine (TdCyd) in adults with advanced solid tumors. Twenty-seven patients received treatment on days 1–5 and 8–12 of 21-day cycles.
Postoperative Neuromuscular Paresis and Overlap Syndrome Related to Immune Checkpoint Inhibitors: A Case Report.
A patient receiving immune checkpoint inhibitor therapy developed extremity paresis after proximal humerus resection and reconstruction.
Long-term effects of a parenting program for advanced cancer: A randomized controlled trial.
This randomized controlled trial evaluated a telephone-delivered, five-session parenting education program for parents with advanced, non-curable cancer who were raising children.
Dexmedetomidine with transition to oral clonidine for stabilization of refractory agitation: A case report.
A 45-year-old man with metastatic medullary thyroid carcinoma was admitted to a palliative care unit with severe opioid-refractory pain, delirium, and agitation that prevented palliative radiation.
Resistance training and protein supplementation in patients with incurable gastroesophageal cancer: a randomized feasibility trial.
This open-label, parallel-group randomized feasibility trial assessed resistance training plus protein supplementation during first-line chemotherapy in patients with incurable gastroesophageal cancer.
A phase 2 study of tipifarnib in children and young adults with tumors harboring HRAS genomic alterations: NCI-COG Pediatric MATCH trial (APEC1621M).
This phase 2 NCI-COG Pediatric MATCH study evaluated intermittent oral tipifarnib in children and young adults with relapsed or refractory solid tumors carrying specified HRAS mutations.
Combining quizartinib with intensive chemotherapy for older patients with newly diagnosed AML: results of the UK NCRI AML18 trial.
The multicentre randomised UK NCRI AML18 trial evaluated quizartinib after intensive chemotherapy, with or without maintenance, in patients older than 60 years with newly diagnosed AML or high-risk myelodysplastic…
Longitudinal remodeling of the tumor-immune microenvironment during regorafenib, nivolumab, and chemotherapy in advanced gastric cancer.
This phase 1b/2 clinical trial evaluated first-line regorafenib, nivolumab, and chemotherapy in 30 patients with mismatch repair-proficient advanced gastric cancer, alongside longitudinal analysis of tumor biopsies.
Resolution of Severe Jaundice Following Hepatic Artery Infusion of Bevacizumab and 5-Fluorouracil With Oral Regorafenib in Metastatic Colorectal Cancer：A Case Report.
A patient with sigmoid colon cancer and recurrent liver metastases, previously treated with surgery, systemic chemotherapy, transcatheter arterial chemoembolization, and radiotherapy, presented with severe jaundice.
A rare neurological adverse event of palbociclib: a chronic inflammatory demyelinating polyneuropathy (CIDP) mimic.
A 43-year-old woman with metastatic HR-positive/HER2-negative breast cancer developed progressive, asymmetric weakness and sensory symptoms about two weeks after starting palbociclib.
Effects of digital stress-management interventions in breast cancer patients 18 months after intervention access.
This randomized controlled trial examined whether app-based cognitive behavioral (CBI) or mindfulness-based (MBI) stress management was associated with improved outcomes 18 months after access began among patients with…
Proton pump inhibitors in prevention of cisplatin-induced nephrotoxicity: a systematic review.
This systematic review assessed whether proton pump inhibitor (PPI) co-administration prevents cisplatin-related kidney injury and whether it is safe.
Coexistence of ARNT::ALK and TPM3::ALK doublegene fusion in an ALK-rearranged renal cell carcinoma with osseous metaplasia.
An adult patient had an ALK-rearranged renal cell carcinoma. The tumor showed varied growth patterns in a mucinous background, with a small peripheral focus of osseous metaplasia.
Effectiveness of home-based exercise interventions on cardiorespiratory fitness and cancer treatment-related cardiovascular toxicity in cancer survivors exposed to cardiotoxic therapies: a systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis of randomized controlled trials assessed structured home-based exercise in cancer survivors exposed to cardiotoxic therapies. Ten trials involving 851 participants were included.
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