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542 articles
October 202624
The Effects of Virtual Reality Group Reminiscence Therapy on Agitation, Cognition, Depression and Social Function in Patients With Alzheimer's Disease.
This assessor-blinded randomised controlled trial evaluated multisensory virtual reality group reminiscence therapy in 60 people with Alzheimer’s disease, comparing twice-weekly 40-minute sessions for 8 weeks with…
The Effects of Force-Velocity Profile-Based Load Prescription on Muscle Power and Functional Performance in Velocity-Deficient Older Adults.
This 12-week randomized controlled trial compared force–velocity profile-guided resistance-training loads in adults aged 65 years or older with a velocity deficit.
Prevalence of fall risk and fear of falling among older adults in the Middle East and North Africa: a systematic review and meta-analysis.
This systematic review and random-effects meta-analysis estimated fall risk and fear of falling among adults aged 60 years or older in the Middle East and North Africa (MENA).
Lurasidone Induced Amphibian Like Buccal Oscillations: A Rare Case of Early Onset Tardive Dyskinesia Like Disorder in a Geriatric Patient with Treatment-Resistant Depression.
A 64-year-old woman with treatment-resistant depression developed floor-of-mouth movements resembling buccal pumping, along with white spots on the inner lower lip and facial puffiness, within 7 days of starting…
The Effects of Mind-Body Exercise on Cognitive Function and Peripheral Blood BDNF in Elderly People With Mild Cognitive Impairment: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis pooled 17 randomized controlled trials involving 1,251 older adults with mild cognitive impairment to assess mind-body exercise and cognition and peripheral blood BDNF.
Magnesium oxide tablets form rigid masses in xanthan gum-based thickeners: A physicochemical hazard revealed by a clinical case.
An older adult with a malignant esophageal stricture developed acute esophageal obstruction from a foreign body identified as a swollen, non-disintegrated magnesium oxide (MgO) tablet.
Expected change: a new concept for monitoring patients on oral bisphosphonates.
This randomized controlled trial evaluated ways to monitor response to oral bisphosphonates in 108 postmenopausal women younger than 85 years treated with alendronate, ibandronate, or risedronate, with calcium and…
Impact of Chatbot-Based Cognitive Training on Cognitive Function and White Matter Integrity in Cognitively Unimpaired Older Adults: Randomized Controlled Trial.
This single-blind randomized controlled trial evaluated chatbot-based cognitive training in 72 cognitively unimpaired older adults.
Changes in gait function associated with cerebral small vessel disease-related cognitive impairment during dual-task walking: a systematic review and meta-analysis.
This systematic review and meta-analysis examined whether dual-task (DT) gait measures distinguish people with cerebral small vessel disease-related cognitive impairment (CSVD-CI) from cognitively unimpaired controls…
Comparative Effectiveness of Digital Exercise-Based Interventions for Improving Balance in Older Adults: Systematic Review and Network Meta-Analysis With GRADE Certainty of Evidence.
This systematic review and network meta-analysis compared five digital exercise-based approaches with conventional exercise (CE) and no treatment (NT) for balance in older adults.
Can Photobiomodulation improve healing of category II-III pressure ulcers in frail older adults? A quasi-experimental 24-month follow-up study.
This quasi-experimental study compared adjunctive photobiomodulation with standard care for category II and III pressure ulcers in frail adults aged 70 years or older receiving municipal home healthcare.
A Bayesian Re-analysis of the GALFLU Trial of High-Dose vs Standard-Dose Influenza Vaccine Against Hospitalization Outcomes.
This Bayesian re-analysis examined hospitalization outcomes in the GALFLU randomized trial, which compared high-dose with standard-dose inactivated influenza vaccine in adults aged 65–79 years.
Impact of age and frailty on the effect of a multimodal individualized long-term intervention after stroke: the last-long trial.
This single-blinded, multicentre randomized controlled trial examined whether age or frailty modified response to a stroke coordinator-led, individualized community intervention.
Informal Caregiver-Observed Fall Risk Indicators and Caregiver Responses to Prevent Falls Among Community-Dwelling Older People: A Systematic Review.
This systematic review synthesized 16 studies of informal caregivers’ observations of fall-risk indicators and their preventive responses among community-dwelling older people.
The entorhinal cortex atrophy score for diagnostic distinction between phases of the Alzheimer's disease continuum.
This systematic review assessed the Entorhinal Cortex Atrophy (ERICA) visual score for distinguishing subjective cognitive decline (SCD), mild cognitive impairment (MCI), and Alzheimer’s disease (AD) dementia.
Feasibility of a Co-Designed Personalized Cognitive Reablement Program Delivered via Digital Voice Assistants for Older Adults Living With Early-Stage Dementia or Mild Cognitive Impairment: Pilot Randomized Controlled Trial.
This nonblinded pilot randomized controlled trial assessed the feasibility and potential effectiveness of VOICE-COG, a personalized cognitive reablement program delivered through digital voice assistants, in adults aged…
A Methodological Framework for a Large Language Model Virtual Companion for Older Adults at Risk of Social Isolation.
This paper presents a methodological framework for developing and evaluating a large language model (LLM)-driven virtual companion for older adults at risk of social isolation.
Systematic review and meta-analysis of risk factors for oral frailty.
This systematic review and meta-analysis examined factors associated with oral frailty across 14 studies involving 12,297 participants, of whom 4,540 had oral frailty.
Agreement Between In-Person and Telephone Application of the Informant Questionnaire on Cognitive Decline in the Elderly.
This methodological study assessed agreement between in-person and telephone administration of the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE), completed by caregivers or family members of older…
Feasibility of a multidimensional interdisciplinary rehabilitation program for people with dementia and their informal primary caregivers - a randomized pilot trial with a caregiver focus.
This randomized pilot trial assessed the feasibility of a person-centred, interdisciplinary rehabilitation program for community-dwelling people with dementia that also provided education and support to informal…
Real-world safety and efficacy of lecanemab in the treatment of Alzheimer's disease: a systematic review and meta-analysis.
This systematic review and meta-analysis pooled real-world studies of lecanemab treatment in people with Alzheimer’s disease, including 37 studies.
Thermographic outcomes of auricular laser acupuncture and auricular seed acupressure in older adults with chronic shoulder pain: an exploratory nonrandomized, nonconcurrent comparison.
This exploratory, open-label, nonrandomized comparison studied 20 adults aged 60–90 years with chronic shoulder pain, allocated by order of entry to auricular laser acupuncture or seed acupressure.
The Effect of Mindfulness-Based Cognitive Therapy on Kinesiophobia in Older Adults with Chronic Knee Osteoarthritis: A Randomized Controlled Trial.
This randomized controlled trial evaluated mindfulness-based cognitive therapy (MBCT) for kinesiophobia in 56 older adults with chronic knee osteoarthritis in Kashan, Iran.
Optimizing exercise prescriptions for older adults with mild cognitive impairment: a dose-response network meta-analysis of modality-dose combinations on executive function.
This Bayesian dose-response network meta-analysis synthesized randomized controlled trials of repeated exercise programmes in adults aged 60 years or older with mild cognitive impairment.
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