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99 articles
October 202615
From Alert to Action: Electronic Practice Advisory Improves DSMES Referrals Over 18 Months.
This cluster-randomized controlled trial in primary care practices in central North Carolina tested whether an electronic health record best practice advisory (BPA) increased referrals to diabetes self-management…
The Improvement in the Clinical Management of Patients Undergoing Palliative Care After Training the Primary Care Team by a Specialized Team: A Systematic Review.
This systematic review assessed whether palliative care training for healthcare professionals in primary care improves symptom assessment and clinical management. Eight studies with varied designs were included.
AI-Based Clinical Decision Support Systems in Primary Care: Systematic Review of Clinical Implementation.
This systematic review assessed the effectiveness and safety of AI-based clinical decision support systems (AI-CDSSs) used by health professionals in primary care, compared with usual care or non-AI decision support.
Advances in physiotherapy for chronic low-back pain: a level I systematic review.
This level I systematic review qualitatively examined randomised controlled trials of physiotherapy programmes for chronic low-back pain (cLBP), identified through searches of PubMed, Web of Science and Embase in August…
Improving Musculoskeletal Care Quality With a Web-Based Clinical Decision Support System in UK Primary Care: Mixed Methods Cluster-Randomized Controlled Trial.
This mixed methods, cluster-randomized controlled trial evaluated CrossCover, a web-based clinical decision support system for adult musculoskeletal consultations in UK general practice.
Acceptability and Feasibility of an Islamic Faith-Based Smoking Cessation Intervention Delivered via WhatsApp for Muslim Smokers in Saudi Arabia: Pilot Randomized Controlled Trial.
This two-arm pilot randomized controlled trial assessed the feasibility, acceptability, and preliminary outcomes of a 21-day Islamic faith-based smoking cessation intervention delivered by WhatsApp to adult Muslim…
Impact of structured sexual health training incorporating standardised patients on health professions students' sexual health communication competence: A single-blind randomised controlled trial in Tanzania.
This single-blind, parallel-group randomised controlled trial evaluated structured sexual health training incorporating standardised patients (SPs) among undergraduate medical and nursing students at a university in…
Continuous Glucose Monitoring in Non-Insulin-Treated Type 2 Diabetes.
This 26-week, multicenter randomized trial compared continuous glucose monitoring (CGM) with routine care in adults with type 2 diabetes not using insulin at 22 US primary care practices.
Efficacy of Ibuprofen Versus Acetaminophen for Acute Fever Management in Febrile Children: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
This systematic review and meta-analysis of randomized controlled trials compared ibuprofen with acetaminophen for acute fever management in children. Seven studies contributed to the quantitative synthesis.
Real-World Effectiveness of AI-Enabled Clinical Decision Support in Primary Care: Systematic Review.
This systematic review synthesized real-world evaluations of clinician-facing AI-enabled clinical decision support in primary and ambulatory care, covering studies published from 2011 through 2025.
Early interventions for primary care patients with stress-related mental ill health: a randomised controlled non-inferiority trial of a nurse-led collaborative care intervention versus cognitive behavioural therapy.
This randomised controlled non-inferiority trial compared nurse-led collaborative care (CC) with psychologist-guided self-help cognitive behavioural therapy (GSH-CBT) in 172 adults with mild to moderate stress-related…
Changes in health literacy following participation in a multidisciplinary primary care intervention for people with chronic pain: a longitudinal cohort study.
This longitudinal cohort study examined changes in health literacy among 43 people with chronic non-cancer pain who completed a personalized, multidisciplinary primary care pain-management intervention.
Effectiveness of a nurse-led telephonic brief intervention to reduce risky alcohol use among women in primary care in Brazil: a randomized controlled trial.
This randomized controlled trial evaluated a nurse-led telephonic brief intervention aimed at reducing risky alcohol use among 151 women in primary care in São Paulo, Brazil.
Implementation of Communication Disability Documentation and Accommodations in Primary Care: A Pragmatic Type III Hybrid Implementation-Effectiveness Trial Protocol.
This article describes the protocol for the DECA study, a pragmatic Type III hybrid implementation-effectiveness trial of communication disability (CD) documentation and accommodation processes in primary care.
Primary care practitioners' experiences managing urinary tract infections: a qualitative evidence synthesis.
This qualitative evidence synthesis explored the experiences of primary care practitioners (PCPs) managing urinary tract infections (UTIs) across various international settings.
September 20269
A pilot randomized controlled trial assessing the feasibility and preliminary effects of a text message intervention to promote secure storage and disposal of prescription opioids.
This two-arm, single-blinded randomized controlled pilot trial tested whether a 45-day text-message intervention could promote safe storage and disposal of prescription opioids among 479 adults prescribed an opioid for…
Summer-pattern seasonal affective disorder: A case study and implications for primary care.
A 35-year-old woman presented with a 3-year history of summer-onset depression, characterized by irritability, insomnia, appetite loss, and psychomotor agitation.
Bridging the gap in caregiver support: A systematic review of screening practices in primary care.
This systematic review examined the use of caregiver burden screening practices in primary care, focusing on studies from 2013 to 2023.
Real-Time Artificial Intelligence Diagnostic Copilot in Simulated Primary Care Consultations: Randomized Simulation Study.
This randomized simulation study evaluated the impact of a real-time, voice-based AI diagnostic assistant on physician diagnostic accuracy in primary care consultations.
Social Support in Group Medical Visits for Chronic Pain in Primary Care.
This randomized controlled trial examined the role of group medical visits in providing social support for primary care patients with chronic pain.
Effect of modernized collaborative care for depression on individual depressive symptoms: A secondary analysis of the eIMPACT trial.
This secondary analysis of the eIMPACT trial evaluated the effects of modernized collaborative care on individual depressive symptoms in 216 primary care patients.
Barriers and enablers to deprescribing from the perspectives of older adults with polypharmacy and their stakeholders: A systematic review of qualitative studies.
This systematic review synthesised qualitative studies on barriers and enablers to deprescribing among older adults with polypharmacy and relevant stakeholders.
BLIS study: a feasibility randomised controlled trial assessing compliance, acceptability and colonisation with different dosing regimens of the probiotic supplement Streptococcus salivarius K12 (Bactoblis) in adults in England.
The BLIS study was a randomized controlled trial assessing the colonization, acceptability, and feasibility of two dosing regimens of the probiotic Streptococcus salivarius K12 in adults with recurrent sore throats in…
Accuracy of type 2 inflammatory biomarkers to diagnose asthma in adults and children: a meta-analysis of 30 studies with prospective validation in an adult primary care cohort.
This systematic review and meta-analysis assessed fractional exhaled nitric oxide (FeNO) and blood eosinophil count (BEC) for diagnosing asthma in adults and children with suspected asthma and normal spirometry, with…
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