Trending archive
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542 articles
May 202616
Creatine monohydrate for lean mass, strength, and bone density in postmenopausal women: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the effects of creatine monohydrate on lean mass, strength, and bone density in postmenopausal women.
Assessment tools for social frailty in older adults based on COSMIN guidelines: A systematic review.
This systematic review evaluated the measurement properties and methodological quality of social frailty assessment instruments for older adults, following COSMIN guidelines.
Association of Social Support With Oral Health in Older Adults: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined the relationship between social support and oral health in older adults aged 75 years and over.
Nimotuzumab Combined With Concurrent Curative Radiotherapy and S-1 in 75 Years and Older Patients With Stage II-IVB Esophageal Squamous Cell Carcinoma: A Phase II Study.
This phase II study evaluated the efficacy and safety of nimotuzumab combined with concurrent radiotherapy and S-1 in patients aged 75 and older with stage II-IVB esophageal squamous cell carcinoma.
Mindful-Compassion Art-Based Therapy for Dementia Care (MCAT-DC): A multicomponent approach to enhancing resilience in dementia family caregivers.
This waitlist randomized controlled trial evaluated a four-week group Mindful-Compassion Art-Based Therapy for Dementia Care program among 102 family caregivers in Singapore.
Anticholinergic Burden as a Modifiable Risk Factor in Cardiac Surgery: A Randomized Controlled Study.
This randomized controlled trial evaluated the impact of reducing perioperative anticholinergic burden on functional recovery in 122 older patients (≥60 years) undergoing coronary artery bypass grafting (CABG).
Protein-enriched foods: A promise older adults will accept? A systematic review of consumer acceptance in later life.
This systematic review examined the acceptance of protein-enriched foods among adults aged 65 and older, analyzing 14 studies.
The Association of Sarcopenic Obesity With Respiratory Function Outcomes in Adults: A Systematic Review and Meta-Analysis.
This systematic review and random-effects meta-analysis examined observational studies of adults with and without sarcopenic obesity and their respiratory function.
Targeted Nrf2 activation improves vascular endothelial function with aging and prevents vascular dysfunction following disuse in younger and older adults.
This randomized controlled trial investigated the effects of PB125, a Nrf2 activator, on vascular endothelial function in 20 younger and 24 older adults.
Opportunistic screening for osteoporosis using chest X-rays and deep learning: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the diagnostic performance of deep learning algorithms applied to chest X-rays for osteoporosis detection, involving 200,796 patients across 12 studies.
Effectiveness of Nurse-Led Interventions in Older Adults With Mild Cognitive Impairment or Dementia: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the effectiveness of nurse-led interventions in older adults with mild cognitive impairment or dementia.
The effects of BASE program on physical fitness and pain related factors in rural late-older women with CLBP: A pilot randomized controlled trial.
This pilot randomized controlled trial evaluated the Body Awareness-Stability-Enhancement (BASE) program's effects on physical fitness and pain in 20 rural women aged ≥75 years with chronic low back pain (CLBP).
Regular Daily Exercise Improves Sarcopenia in Elderly Patients.
This 12-week randomized controlled trial assessed multicomponent exercise in adults aged 60–75 years with sarcopenia. Participants were assigned to control or postprandial resistance and aerobic training for 37 minutes…
Multimodal intervention benefits: Responder analysis of J-MINT PRIME Kanagawa trial.
The J-MINT PRIME Kanagawa trial, a randomized controlled trial, explored a multimodal intervention for dementia prevention in 188 older adults.
Feasibility and exploratory cognitive outcomes of three exercise modalities in oldest-old adults in assisted living facilities: A 24-week pilot randomized controlled trial.
This pilot randomized controlled trial evaluated the effects of aerobic, resistance, and mind-body exercises on cognitive function in 76 residents aged ≥80 in an assisted living facility over 24 weeks.
Comparing the Effects of Cognitive and Physical Training on Cognitive Function and Brain Activation in People With Mild Cognitive Impairment and Mild Dementia: A Randomized Controlled Trial.
This randomized controlled trial evaluated the effects of cognitive training (CT) and physical training (PT) on cognitive function and brain activation in older adults with mild cognitive impairment or mild dementia.
April 20268
Acute metabolic responses to breaking up sedentary time in older adults.
This randomized controlled trial examined the effects of interrupting sedentary time with light activity on metabolic flexibility in 12 sedentary older adults.
The diagnostic accuracy of blood biomarkers for sarcopenia, sarcopenic obesity, and osteosarcopenia: a meta-analysis.
This meta-analysis evaluated the diagnostic accuracy of blood biomarkers for sarcopenia and related conditions across various populations.
Coadministration of mRNA-1345 RSV vaccine with high-dose quadrivalent influenza vaccine in adults aged 65 and older: An observer-blinded, placebo-controlled, randomized, phase 3 trial.
This phase 3 randomized trial assessed the safety and immunogenicity of the mRNA-1345 RSV vaccine coadministered with high-dose quadrivalent influenza vaccine in adults aged 65 and older (n=1900).
Validity and reliability of an automated fall risk assessment system using a depth camera in community-dwelling adults: A proof-of-concept pilot study.
This proof-of-concept pilot study evaluated the validity and reliability of a consumer-grade depth camera system for automated fall risk assessment in 39 community-dwelling adults.
Toward Precision Psychiatry: Using Clinical and Pharmacokinetic Data to Increase Antidepressant Dose or Change Treatment in Late-Life Depression.
This randomized controlled trial investigated the use of clinical, pharmacogenetic, and pharmacokinetic data to guide treatment decisions in older patients with major depressive disorder (MDD) who did not fully respond…
Promoting digital memory aid use in older adults with cognitive concerns: A pilot randomized controlled trial of adaptive web-based training.
This pilot randomized controlled trial evaluated a web-based training platform for older adults with cognitive concerns, comparing self-guided support to clinician-supported sessions.
Brief intervention for inappropriate z-hypnotics use in older adults: a before and after intervention study in primary care.
This randomized controlled trial evaluated the long-term effects of a brief intervention for inappropriate z-hypnotic use in older adults within primary care.
Efficacy of adjunctive intermittent theta-burst stimulation on depressive and insomnia symptoms in elderly patients with depression and comorbid insomnia: A randomized, sham-controlled trial.
This randomized, sham-controlled trial investigated the effects of intermittent theta-burst stimulation (iTBS) on depressive and insomnia symptoms in 36 elderly patients with late-life depression and comorbid insomnia.
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