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937 articles
August 202624
Efficacy of probiotic and synbiotic supplementation on antibiotic use duration and risk of postoperative infection in patients undergoing gastrointestinal and cancer-related surgery: An umbrella review of meta-analyses.
This umbrella review assessed the impact of synbiotic and probiotic supplementation on antibiotic use duration and postoperative infection risk in patients undergoing gastrointestinal and cancer-related surgery.
Association of computed tomography-derived body composition and complications after radical gastrectomy for gastric cancer: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the association between computed tomography-derived body composition parameters and postoperative complications (POCs) in gastric cancer patients.
Decision for preservation or ligation of aberrant left hepatic artery using fluorescence imaging in minimally invasive gastrectomy: a prospective nonrandomized comparative study.
This multicenter, prospective, nonrandomized comparative study evaluated the use of near-infrared fluorescence imaging to guide the preservation or ligation of the aberrant left hepatic artery (ALHA) during minimally…
Gastric lipoma causing ball-valve syndrome successfully treated by endoscopic submucosal dissection.
A 52-year-old woman presented with postprandial epigastric discomfort and nausea. CT showed a low-attenuation mass extending from the gastric antrum to the duodenal bulb; endoscopy found a broad-based subepithelial…
Severe Acute Cholera Infection Mimicking Decompensated Liver Cirrhosis and Triggering Autoimmune Hepatitis.
An 18-year-old previously healthy Sudanese refugee developed severe acute cholera with deep cholestatic jaundice, disseminated intravascular coagulation, hemolysis, hepatic encephalopathy, and ascites.
Cryoablation versus radiofrequency ablation for hepatocellular carcinoma: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the effectiveness and safety of cryoablation (CA) versus radiofrequency ablation (RFA) in treating hepatocellular carcinoma (HCC).
Efficacy and safety of pantoprazole for stress-ulcer prophylaxis in critically ill patients: A systematic review and Meta-analysis of randomized controlled trials.
This systematic review and meta-analysis evaluated the efficacy and safety of pantoprazole for stress-ulcer prophylaxis in critically ill patients, including both adults and children.
Food-derived extracellular vesicles as delivery platforms for medicine-food homology components in metabolic syndrome.
This systematic review examines the role of food-derived extracellular vesicles (FDEVs) as delivery systems for medicine-food homology components (MFHCs) in managing diet-induced obesity and metabolic syndrome.
Bridging in vitro buoyancy to clinical performance: A PBPK-driven analysis of once-daily Bepotastine gastro-retentive tablet in beagles and humans.
This randomized controlled trial evaluated a low-density gastro-retentive tablet of Bepotastine in beagles and humans. The study found that the tablet achieved 95.7% systemic exposure compared to a twice-daily…
Comparison of the outcomes of ileal pouch-anal anastomosis and ileorectal anastomosis for patients with familial adenomatous polyposis: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated outcomes of ileal pouch-anal anastomosis (IPAA) versus ileorectal anastomosis (IRA) in 4700 patients with familial adenomatous polyposis.
The Effect of a Repetitive Feeding Challenge With Carbohydrate Versus Fat on Markers of Gastrointestinal Integrity and Systemic Outcomes in Response to Endurance Exercise.
This randomized controlled trial examined whether a 7-day repetitive feeding challenge with fat, compared with carbohydrate (CHO), affected gastrointestinal integrity and systemic inflammatory markers during endurance…
Bile Cell-Free DNA as a Tumor-Proximal Source for Molecular Profiling of Biliary Tract Cancer: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed bile cell-free DNA (cfDNA) for molecular profiling in biliary tract cancer. Eight studies involving 271 patients were included.
Matching-adjusted indirect comparison of fruquintinib versus ramucirumab in advanced gastric or gastroesophageal junction adenocarcinoma.
This study conducted a matching-adjusted indirect comparison of fruquintinib plus paclitaxel versus ramucirumab plus paclitaxel in patients with advanced gastric or gastroesophageal junction adenocarcinoma.
Efficacy and safety of endoscopic resection followed by chemoradiotherapy with S-1 plus cisplatin for esophageal cancer.
This single-centre, single-arm exploratory phase II study assessed endoscopic resection (ER) followed by chemoradiotherapy (CRT) with S-1 plus cisplatin in patients with superficial esophageal squamous cell carcinoma…
Impact of structured exercise-based regimen on frailty in pediatric cirrhosis: A randomized controlled trial.
This randomized controlled pilot trial assessed a structured exercise regimen in children aged 9–18 years with cirrhotic liver disease and frailty, comparing exercise plus standard medical therapy (SMT) with SMT alone.
EQ-5D health utility gains with once-weekly semaglutide 2.4 mg in people with MASH and F2/F3 fibrosis: An analysis of ESSENCE.
This exploratory analysis of Week 72 data from the Phase III, randomized, double-blind, placebo-controlled ESSENCE trial assessed mapped EQ-5D health utility in adults with biopsy-confirmed MASH and F2 or F3 fibrosis.
Efficacy and safety of once-weekly semaglutide 2·4 mg in Chinese adults with overweight or obesity (STEP 12): a randomised, double-blind, placebo-controlled, multicentre, phase 3b trial.
This phase 3b randomized, double-blind, placebo-controlled trial evaluated the efficacy and safety of once-weekly semaglutide 2.4 mg in Chinese adults with overweight or obesity.
Meta-Analysis: Prevalence of Non-Helicobacter pylori, Non-NSAID Peptic Ulcer Disease.
This meta-analysis examined the prevalence of non-H. pylori, non-NSAID peptic ulcer disease (PUD) in adults, analyzing 92 studies with 60,816 patients. The findings revealed that 13.0% of overall PUD cases were non-H.
High-animal protein and high-plant protein meals differentially alter postprandial plasma amino acid concentrations but not glucose homeostasis in people with overweight/obesity in a randomized, crossover, single-meal study.
This randomized crossover trial examined the effects of high-animal protein (HAP) and high-plant protein (HPP) meals on postprandial plasma amino acid and glucose levels in individuals with overweight/obesity.
Small intestinal compared with colonic short-chain fatty acid delivery drives distinct systemic concentrations and endocrine responses in humans: a randomized, crossover trial.
This randomized, crossover trial investigated the effects of short-chain fatty acid (SCFA) delivery to the small intestine versus the colon in 28 healthy adults.
Inflammation hinders anabolic potential of nutritional support in cancer: findings from the Protein Recommendation to Increase Muscle (PRIMe) trial.
The PRIMe trial analyzed the impact of baseline inflammation on the effectiveness of high-protein nutritional support in patients with stage II-IV colorectal cancer.
Diffuse Long-segment Colonic Wall Thickening Mimicking Abdominal Tuberculosis: A Diagnostic Challenge Revealing Signet Ring Cell Carcinoma in a 24-year-old Male.
A 24-year-old man with long-standing abdominal pain had contrast-enhanced CT showing target-like diffuse bowel-wall thickening from the terminal ileum through the entire transverse colon, with ascites and omental…
Gastric Variceal Bleed in Pregnancy.
A 25-year-old primigravida at 18 weeks’ gestation presented with hematemesis and melena, with pallor, tachycardia, splenomegaly, anemia, and thrombocytopenia. Doppler ultrasound showed a portal cavernoma.
Comparison of Keverprazan-based versus esomeprazole-based dual therapy for initial treatment of Helicobacter pylori infection: a prospective, multicenter, randomized controlled trial.
This multicenter, randomized controlled trial compared 14-day keverprazan-amoxicillin therapy (KA) with esomeprazole-amoxicillin therapy (EA) in 264 treatment-naive adults with Helicobacter pylori infection.
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