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464 articles

April 20262

March 20268

Clinical ResearchInternal Medicine (General)Open access

Incidence of and Risk Factors for Repeat Adverse Drug Events: A Systematic Review.

This systematic review and meta-analysis examined the incidence of and risk factors for repeat adverse drug events (ADEs), defined as harm occurring after medication re-exposure.

J Patient SafMar 25, 2026Read summary
Clinical ResearchInternal Medicine (General)Open access

Examining the characteristics of patients with long-term impaired work ability in primary health care - a cross-sectional study.

This cross-sectional study described 243 primary healthcare patients in Sweden with recurrent or long-term sick leave or health-related unemployment, recruited through a cluster-randomized trial across 40 primary care…

Scand J Prim Health CareMar 23, 2026Read summary
Clinical ResearchPsychiatryOpen access

Heart Rate Variability in Anorexia Nervosa: A Systematic Review and Meta-Analysis on the Moderating Role of Measurement Duration and Clinical Stage.

This systematic review and meta-analysis assessed heart rate variability (HRV) in people with anorexia nervosa (AN) compared with healthy controls, including differences by clinical stage and recording duration.

Eur Eat Disord RevMar 23, 2026Read summary
Clinical ResearchInfectious Diseases

A Systematic Review of Machine Learning Models For Sepsis Prediction: An Appraise-Ai Approach.

This systematic review assessed machine-learning models for sepsis prediction and the quality of the supporting research. It included 53 studies, mainly retrospective cohort studies published from 2020 to 2024, and…

ShockMar 20, 2026Read summary
Clinical ResearchEndocrinology

Effects of Moderate-Frequency Resistance Training on Cardiometabolic Risk Factors in Adults With Overweight or Obesity: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed moderate-frequency resistance training (2–3 sessions per week) in nonathletic adults with overweight or obesity.

Obes RevMar 17, 2026Read summary
Case ReportEndocrinology

Euglycemic Diabetic Ketoacidosis Following Treatment with Tirzepatide and SGLT-2 Inhibitors: A Case Report and Literature Review.

A patient receiving tirzepatide and an SGLT-2 inhibitor developed euglycemic diabetic ketoacidosis while continuing both medications during a sick-day condition.

Intern MedMar 17, 2026Read case
Clinical ResearchAnesthesiology

High-Flow Nasal Oxygen and the Risk of Gastric Insufflation: A Systematic Review and Meta-Analysis Supplemented by Narrative Synthesis.

High-flow nasal oxygen (HFNO) generates positive airway pressure, raising concerns about gastric insufflation and aspiration risk.

Anesth AnalgMar 4, 2026Read summary
Case ReportInternal Medicine (General)

Successful Immunosuppressive Therapy for Aseptic Abscess Syndrome Presenting with a Fever of Unknown Origin.

A 70-year-old woman presented with recurrent fever, multiple colonic aphthae, and painful nodules on her limbs. CT showed multiple splenic lesions, and aspiration yielded white purulent fluid, initially suggesting…

Intern MedMar 3, 2026Read case

February 20266

Clinical ResearchEndocrinologyOpen access

Changes in hemoglobin levels and cardiometabolic health in adults with metabolic syndrome - a secondary outcome analysis of a six-month randomized controlled trial.

This secondary outcome analysis of a six-month randomized controlled trial examined whether hemoglobin (Hb) changes tracked cardiometabolic changes in 64 adults with metabolic syndrome participating in a…

Ann MedFeb 28, 2026Read summary
Clinical ResearchPulmonology

High-flow oxygen therapy in comparison with low-level pressure support ventilation for spontaneous breathing trials: A two-center, non-inferiority, randomized controlled study.

This two-centre, open-label, non-inferiority randomised controlled trial compared high-flow oxygen therapy (HFOT) with low-level pressure support ventilation (PSV) during 30-minute spontaneous breathing trials (SBTs) in…

PulmonologyFeb 18, 2026Read summary
Clinical ResearchGeriatricsOpen access

Views and Experiences of People With Dementia, Informal Caregivers and Professionals on Eating and Drinking Difficulties: A Qualitative Systematic Review.

This qualitative systematic review examined how people with dementia, informal caregivers and professionals experience eating and drinking difficulties.

J Adv NursFeb 18, 2026Read summary
Case ReportCardiology

Rehabilitation Course Through Compassionate Use of JenaValve Trilogy Heart Valve System in a Patient With Left Ventricular Assist Device: A Case Study.

A 47-year-old man with a destination HeartMate 3 LVAD developed methicillin-susceptible Staphylococcus aureus bacteremia and severe aortic insufficiency, leading to cardiogenic shock.

ASAIO JFeb 10, 2026Read case
Clinical ResearchNeurology

Sex differences in the clinical and surgical management after intracerebral hemorrhage: A post hoc analysis of the INTERACT3 clinical trial.

This post hoc analysis of the international, stepped-wedge cluster-randomised INTERACT3 trial examined sex differences in acute clinical and surgical care among 7,036 adults with intracerebral hemorrhage; 36% were…

Int J StrokeFeb 5, 2026Read summary
Case ReportRheumatology

Macrophage Activation Syndrome Associated with Adult-onset Still's Disease Successfully Treated with Plasma Exchange and Canakinumab.

A 20-year-old Japanese woman with adult-onset Still’s disease developed macrophage activation syndrome despite prednisolone and tocilizumab.

Intern MedFeb 1, 2026Read case

January 20268

Clinical ResearchInternal Medicine (General)Open access

Prevalence and incidence of post-intensive care syndrome among intensive care unit survivors: a systematic review and meta-analysis.

This systematic review and random-effects meta-analysis examined post-intensive care syndrome (PICS) among intensive care unit survivors, synthesising 34 cross-sectional and cohort studies with 6230 participants.

Ann MedJan 28, 2026Read summary
Case ReportEndocrinologyOpen access

A Case of Diagnostic Delay: Autoimmune Adrenalitis Mimicking Functional Gastrointestinal Disorder.

A 23-year-old man with previously treated tuberculous meningitis presented with recurrent vomiting, generalized weakness, and altered behavior. He was hypotensive and drowsy, with hyponatremia and hyperkalemia.

Ann Afr MedJan 22, 2026Read case
Clinical ResearchGastroenterology

Low-Dose Aspirin Continuation During Gastric Endoscopic Submucosal Dissection in Patients With Low Thrombotic Risk: A Randomized Trial.

This randomized trial compared continuing versus discontinuing low-dose aspirin around gastric endoscopic submucosal dissection in patients with gastric mucosal neoplasms and low thrombotic risk.

Am J GastroenterolJan 22, 2026Read summary
Case ReportGastroenterology

The Endoscopic Removal of a Gastric Bezoar Made of Sodium Zirconium Cyclosilicate Hydrate.

A 77-year-old woman receiving intensive care for acute adrenal insufficiency developed a 37-mm gastric bezoar after sodium zirconium cyclosilicate hydrate (SZC) was administered through a nasogastric tube.

Intern MedJan 15, 2026Read case
Clinical ResearchInternal Medicine (General)Open access

Risk factors of venous thromboembolism in ICU patients: a systematic review and meta-analysis.

This systematic review and meta-analysis examined factors associated with venous thromboembolism (VTE) among patients admitted to intensive care units. Of 2465 studies identified, 30 were included in pooled analyses.

Ann MedJan 13, 2026Read summary
Clinical ResearchNeurologyOpen access

Comparison of the predictive performance of systemic immune-inflammation index and neutrophil-to-lymphocyte ratio for three-month poor functional outcome in ischemic stroke: a systematic review and meta-analysis.

This systematic review and meta-analysis compared the prognostic performance of the systemic immune-inflammation index (SII) and neutrophil-to-lymphocyte ratio (NLR) for poor functional outcome at three months after…

Ann MedJan 12, 2026Read summary
Clinical ResearchCardiology

Methodological insights and correlations of short-term BP variability indices.

This analysis examined how four indices of short-term systolic blood pressure variability relate to one another in 65 hypertensive participants aged ≥40 years with obstructive sleep apnoea, using baseline 24-hour…

Blood PressJan 4, 2026Read summary
Clinical ResearchGastroenterology

The effectiveness and safety of naldemedine in treating opioid-induced constipation among non-cancer adult patients: updated meta-analysis.

This systematic review and meta-analysis assessed naldemedine for opioid-induced constipation in non-cancer adults, pooling eight randomised controlled trials from six studies.

Expert Opin Drug SafJan 2, 2026Read summary

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