Trending archive
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542 articles
June 20263
Effects of exercise on metabolic risk, cardiovascular fitness, and body composition in elderly women of the past decade: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the effects of exercise on metabolic risk, cardiovascular fitness, and body composition in healthy elderly women.
Interventions to Reduce Loneliness in Informal Caregivers of People With Dementia: A Systematic Review.
This systematic review evaluated interventions aimed at reducing loneliness in informal caregivers of dementia patients. Eight studies were analyzed, with three being randomized controlled trials.
A pragmatic randomized trial to evaluate the vaccine effectiveness of bivalent RSV prefusion F vaccine for preventing RSV hospitalizations in adults (DAN-RSV): Trial design update.
The DAN-RSV trial is a pragmatic randomized controlled trial assessing the effectiveness of the bivalent RSV prefusion F vaccine in preventing RSV-related hospitalizations among adults.
May 202621
Mental Health Stereotypes and Aging: Effects on Mood and Decision Making.
This randomized controlled trial examined the impact of negative aging stereotypes on the mood, risk tolerance, and patience of older adults (mean age = 68.9).
Pharmacological and non-pharmacological treatments for chronic insomnia in perimenopausal and postmenopausal women: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated pharmacological and non-pharmacological treatments for chronic insomnia in perimenopausal and postmenopausal women.
Safety and durability of influenza and SARS-CoV-2 antibody responses through 6 months after a single dose of mRNA-1083, a multicomponent influenza and COVID-19 vaccine, in adults ≥50 years.
This phase 3 randomized controlled trial evaluated the safety and immunogenicity of mRNA-1083, a multicomponent vaccine for influenza and SARS-CoV-2, in adults aged ≥50 years.
Physical therapy for urinary incontinence in older women: A systematic review.
This systematic review evaluated randomized controlled trials of physical therapy interventions for urinary incontinence in women aged 60 and older.
Risk factors for suicidal behaviour in people with dementia: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the risk factors for suicidal behavior in people with dementia (PwD). It found that PwD have a 62% increased risk of suicidal behavior compared to non-dementia controls…
Cannabinoids Treatment for Agitation in Alzheimer's Disease: A Systematic Review and Meta-Analysis With Bayesian and Sequential Trial Analyses.
This systematic review and meta-analysis evaluated the efficacy and safety of cannabinoid-based therapies for agitation in Alzheimer's disease, involving 221 participants across seven studies.
Effect of exercise interventions on hand grip and TUG in older adults: A network meta-analysis of randomized controlled trials.
This network meta-analysis evaluated the effects of various exercise interventions on hand grip strength and functional mobility in older adults.
Wearable devices for improving medication adherence in older adults with chronic conditions: A systematic review.
This systematic review evaluated the impact of wearable devices on medication adherence in adults aged 65 and older with chronic conditions.
Efficacy and safety of donanemab in the European eligible population: TRAILBLAZER-ALZ 2 post-hoc analyses.
This post-hoc analysis of the TRAILBLAZER-ALZ 2 trial evaluated the efficacy and safety of donanemab in European Union-eligible patients with early symptomatic Alzheimer's disease.
Supporting Physical Activity and Quality of Life in Older Adults with Coronary Heart Disease: Development of a Web-Based Nursing Intervention.
This clinical trial describes the development of 'Changeons ensemble', a web-based nursing intervention aimed at promoting physical activity and quality of life in older adults with coronary heart disease (CHD).
Applying Implementation Science Methods to Prospectively Track the Adaptation of an Evidence-Based Deprescribing Intervention for Use in a New Health System and Country.
This pragmatic clinical trial evaluated the adaptation of the STOP-FALLS deprescribing intervention for older adults within the Kaiser Permanente Washington health system.
Advantages of artificial saliva containing Cuminum cyminum and Zingiber officinale on hemodialysis patients with xerostomia: Randomized clinical trials.
This randomized controlled trial evaluated the efficacy and safety of herbal artificial saliva (HAS) containing cumin and ginger in hemodialysis patients with xerostomia.
Osteoporotic fractures prevalence in Latin American countries: A systematic review of literature and meta-analysis.
This systematic review and meta-analysis examined the prevalence of osteoporotic fractures (OF) in Latin America, analyzing data from 22 studies involving 1,182,219 participants.
Cost-effectiveness of integrated prevention for late-life depressive symptoms: Real-world findings from a large-scale pragmatic trial ("JoyAge").
This pragmatic non-randomised controlled trial evaluated the cost-effectiveness of the JoyAge integrated prevention program for late-life depression in a sample of 3,416 participants.
Adherence and effectiveness of multicomponent exercise fall prevention programmes across delivery formats in community-dwelling older adults: a systematic review and multilevel meta-analysis.
This systematic review and multilevel meta-analysis evaluated the effectiveness of multicomponent exercise programmes for fall prevention in community-dwelling adults aged 60 and older.
Determinants of social participation among community-dwelling older adults: A mixed-methods systematic review.
This mixed-methods systematic review examined determinants of social participation among community-dwelling older adults, analyzing 99 studies.
Efficacy and Implementation of a Theory-Underpinning Needs-Oriented mHealth Supportive Program for Family Caregivers of Community-Dwelling Frail Older Adults (Hi-Care): A Randomized Controlled Trial.
This randomized controlled trial evaluated the Hi-Care mHealth program for family caregivers of community-dwelling frail older adults.
Treating insomnia in mild cognitive impairment: a novel approach combining transcranial magnetic stimulation with cognitive behavioral therapy.
This Phase I/II clinical trial investigates the feasibility and preliminary efficacy of combining repetitive transcranial magnetic stimulation (rTMS) with cognitive behavioral therapy for insomnia (CBT-I) in 30…
The Impact of Taiwan's Nationwide Postacute Care Program on Functional Recovery, Health Care Utilization, and Cost-Effectiveness for Patients With Stroke: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the impact of Taiwan's Post-Acute Care for Cerebrovascular Disease (PAC-CVD) program on stroke survivors.
A Systematic Review and Meta-Analysis of the Global Prevalence of Dry Mouth in Older Adults.
This systematic review and meta-analysis assessed the global prevalence of xerostomia and salivary gland hypofunction (SGH) in older adults.
Associations Between Multimorbidity, Polypharmacy and Oral Conditions in Older Adults: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined the relationship between multimorbidity, polypharmacy, and oral health in older adults aged 75 and older.
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