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2000 articles
October 202624
Clinical outcomes of early versus standard liver transplantation in patients with alcohol-related liver disease: a meta-analysis.
This meta-analysis compared early and standard liver transplantation in patients with alcohol-related liver disease. It included 12 studies and 2323 patients.
Pulmonary cryptococcosis mimicking metastatic progression despite systemic disease stability in advanced colon cancer: A case report and literature review.
A patient with advanced colon cancer undergoing chemotherapy presented with new pulmonary nodules on imaging, despite stable systemic disease and declining tumor markers.
Molecular Profiling of Tisotumab Vedotin-Treated Patients Identifies Immune Pathways Associated with Clinical Activity.
This phase II multicenter trial evaluated the efficacy of tisotumab vedotin (TV) in patients with recurrent or metastatic cervical cancer (r/mCC).
Xiaoaiping Injection Combined with Chemotherapy Versus Chemotherapy Alone for Breast Cancer: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed the efficacy and safety of Xiaoaiping Injection (XAP) combined with chemotherapy versus chemotherapy alone in breast cancer patients.
Avutometinib, Abemaciclib, and Fulvestrant in Patients with HR+/HER2- Metastatic Breast Cancer Previously Treated with CDK4/6 Inhibitor: A Single-Arm Phase I Trial.
This single-arm phase I trial evaluated the combination of avutometinib, abemaciclib, and fulvestrant in 16 patients with HR+/HER2- metastatic breast cancer who had previously progressed on CDK4/6 inhibitors.
Intrathecal Allogeneic B7-H3-Targeted CAR γδ T Cells for Leptomeningeal Metastasis from Solid Tumors: Safety, Efficacy, and Immunologic Dynamics in a Phase I Trial.
This phase I trial evaluated the safety and efficacy of intrathecal QH104, an allogeneic B7-H3-targeted CAR γδ T-cell therapy, in 3 patients with leptomeningeal metastasis from solid tumors.
Mastectomy and sentinel lymph node biopsy in a patient with left-sided breast cancer and Poland syndrome.
An elderly woman with left-sided Poland syndrome presented with breast cancer detected during routine imaging for malignant melanoma.
Osimertinib plus Gefitinib in Patients with EGFR-Mutated Advanced Non-Small Cell Lung Cancer and EGFR (C797X) Mutation Following First-Line Osimertinib: ORCHARD.
The ORCHARD study was a phase II trial assessing the efficacy of osimertinib plus gefitinib in patients with EGFR-mutated advanced non-small cell lung cancer (NSCLC) and EGFR C797X mutation after progression on…
The Effectiveness of Incentives on Cancer Screening among Indigenous Populations: Systematic Review.
This systematic review assessed the effectiveness of various incentives on cancer screening participation among Indigenous populations.
A randomized trial to evaluate the effect of epigallocatechin gallate (EGCG) on EBV reactivation in patients with nasopharyngeal carcinoma in remission -the TCOG T2312 study.
This multicentre randomized controlled trial tested whether epigallocatechin gallate (EGCG) reduces Epstein-Barr virus (EBV) reactivation in patients with nasopharyngeal carcinoma (NPC) in remission after…
Maxillofacial prosthetic management of oral incompetence following commando surgery and partial maxillectomy: A clinical report.
A patient who underwent commando surgery and partial maxillectomy for squamous cell carcinoma presented with significant facial defects, oral incompetence, and discomfort.
Well-differentiated SMARCB1-deficient Pancreatic Malignancy With Indolent Liver Metastases.
A 66-year-old woman underwent distal pancreatectomy for a pancreatic tail malignancy, later developing liver metastases six years post-surgery.
Phase I Trial of GPC3-Targeted TCR Fusion Construct, CT0180, in Patients with Advanced Hepatocellular Carcinoma.
This Phase I open-label trial evaluated the safety and preliminary efficacy of CT0180, a GPC3-targeted TCR fusion construct, in patients with advanced hepatocellular carcinoma (HCC) who had progressed on standard…
A Randomized, Nivolumab-Controlled, Phase II Biomarker Study of Lomvastomig and Tobemstomig in Advanced or Metastatic Squamous Cell Carcinoma of the Esophagus.
This phase II randomized controlled trial evaluated the efficacy of bispecific antibodies lomvastomig and tobemstomig against nivolumab in 190 checkpoint inhibitor-naïve patients with advanced esophageal squamous cell…
Opioid Use and Family Members' Experiences of Opioids in Paediatric Cancer Pain Management: An Integrative Review.
This integrative review analyzed opioid use in pediatric cancer pain management and family members' experiences. Sixteen peer-reviewed articles were reviewed, revealing that morphine and fentanyl are the most commonly…
Efficacy and Safety of PD-1/PD-L1 Inhibitors Combined With Anti-Angiogenic Tyrosine Kinase Inhibitors for Recurrent or Metastatic Nasopharyngeal Carcinoma: A Systematic Review and Single-Arm Meta-Analysis.
This systematic review and meta-analysis evaluated the efficacy and safety of PD-1/PD-L1 inhibitors combined with anti-angiogenic tyrosine kinase inhibitors in 357 patients with recurrent or metastatic nasopharyngeal…
Immersive Virtual Reality and Anxiety, Nausea, and Vomiting in Children With Cancer: An RCT.
This randomized controlled trial evaluated the impact of immersive virtual reality (IVR) on anxiety, anticipatory nausea, and chemotherapy-induced nausea and vomiting (CINV) in pediatric cancer patients aged 6-12…
Three versus six weeks of corticosteroids for mild immune-related pneumonitis: a randomized trial.
This randomized controlled trial evaluated the efficacy of a 3-week versus a 6-week corticosteroid taper in patients with mild immune-related pneumonitis.
Primary tongue leiomyosarcoma.
A male patient in his mid 50s presented with a non-healing ulcer on the right lateral border of the tongue, accompanied by impaired tongue movement.
First-trimester pregnancy-associated breast cancer managed without pregnancy termination: a report with long-term follow-up.
A patient diagnosed with breast cancer in the first trimester opted to continue her pregnancy rather than terminate it. She underwent total mastectomy and axillary lymph node dissection, with chemotherapy initiated…
Pembrolizumab plus Chemotherapy for Synchronous Multiple Primary Esophageal and Gingival Squamous Cell Carcinomas.
A 68-year-old man presented with synchronous squamous cell carcinomas of the esophagus and mandibular gingiva. He received pembrolizumab combined with cisplatin and 5-fluorouracil, leading to a clinical complete…
Malignant phyllodes tumour with spinal metastasis presenting as cauda equina syndrome.
A female in her early 50s with a history of borderline phyllodes tumour underwent right mastectomy and adjuvant radiotherapy.
Toripalimab consolidation after chemoradiotherapy in limited-stage small cell lung cancer: a phase II, randomized controlled study (GASTO-1052A).
This phase II randomized controlled trial evaluated the efficacy and safety of toripalimab consolidation after chemoradiotherapy in patients with limited-stage small cell lung cancer (LS-SCLC).
Exposure-Response Analyses of Ropeginterferon Alfa-2b in Essential Thrombocythemia.
This meta-analysis examined the population pharmacokinetics and pharmacodynamics of ropeginterferon alfa-2b in patients with essential thrombocythemia (ET).
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