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542 articles
June 202624
Jianpi Qiangji granules improve muscle function in sarcopenia and reshape bile acid metabolism: A randomized double-blind positive-controlled trial.
This exploratory, double-blind, double-dummy, positive-controlled randomized trial compared Jianpi Qiangji granules (JQG) with calcitriol in 80 older patients with sarcopenia treated for 12 weeks.
World Health Organization Healthy Ageing model applied to adults with cerebral palsy: A systematic review of reported intrinsic capacity measures.
This systematic review synthesized quantitative measures of the World Health Organization’s intrinsic capacity domains in adults with cerebral palsy (CP), using studies published from 2013 to 2023 and an updated search…
Improving infection control in nursing homes: Enhanced barrier precautions and multidrug-resistant organism colonization.
This multicenter clinical trial evaluated the effectiveness of enhanced barrier precautions (EBP) in identifying multidrug-resistant organism (MDRO) colonization among 580 short-stay nursing home residents.
Clinically indicated versus routine replacement of peripheral intravenous cannulas in elderly patients: Secondary analysis of a multi-center randomized controlled trial in mainland China.
This secondary analysis of a multicenter randomized controlled trial evaluated the outcomes of clinically indicated versus routine replacement of peripheral intravenous cannulas (PIVCs) in 1805 elderly patients.
Validated Measures of Agitation in Neurocognitive Disorders: A Systematic Review of 41 Scales and Their Alignment With International Psychogeriatric Association Criteria.
This systematic review evaluated 41 validated agitation scales in neurocognitive disorder populations, assessing their alignment with the International Psychogeriatric Association (IPA) criteria.
Dose-response effects of isometric wall squats on postexercise hypotension in older women with hypertension.
This randomized controlled trial evaluated the effects of two doses of isometric wall squats (IWS) on postexercise hypotension in 30 older women with systemic arterial hypertension.
Deprescribing Interventions in Older Adults with Polypharmacy: A Systematic Review of Economic Evaluations.
This systematic review evaluated the economic evidence of deprescribing interventions in older adults (≥65 years) with polypharmacy.
A Comparison of Fixed Percentage of One-Repetition Maximum, Rating of Perceived Exertion, and Last Repetition Velocity-Based Training Load Prescription on Muscular Adaptations in Older Adults.
This randomized controlled trial compared three resistance training load prescriptions—fixed percentage of one-repetition maximum (PBT), rating of perceived exertion (RBT), and last repetition velocity-based training…
Experiences and needs of informal caregivers for respite care: A mixed-methods systematic review.
This mixed-methods systematic review examined the experiences and needs of informal caregivers regarding respite care, synthesizing data from 33 studies.
From laboratory to daily life assessment: A systematic review and meta-analysis of gait speed discrepancies in healthy older adults.
This systematic review and meta-analysis examined gait speed discrepancies between laboratory and real-world settings in healthy older adults.
Characteristics and Reasons for Non-attendance at Exercise Therapy and Self-Management Support Among Patients With Multimorbidity. An Exploratory Cross-sectional Study From the MOBILIZE Trial.
This exploratory cross-sectional study from the MOBILIZE randomized controlled trial examined characteristics of 114 patients with multimorbidity assigned to exercise therapy and self-management support.
Gallbladder Volvulus Presenting as Acute Cholecystitis: Diagnostic Challenges and the Need for Early Surgical Intervention.
An elderly patient presented with signs and symptoms resembling acute cholecystitis. At laparoscopy, the gallbladder was found to have torsion of its cystic pedicle, with resulting ischemia, establishing gallbladder…
Differential utility of immediate versus delayed memory measures for the identification of episodic memory impairment: Systematic review and meta-analysis.
This systematic review and meta-analysis compared immediate with delayed recall for distinguishing patients with suspected or known episodic memory impairment from healthy controls.
Are psychotropic medications equivalent in fall risk among nursing home residents? A meta-analysis of pharmacologic subtypes and polypharmacy effects.
This meta-analysis examined the fall risk associated with various psychotropic medications in nursing home residents. It included 20 studies and found that typical antipsychotics (OR = 1.66) and atypical antipsychotics…
Effects of Acute Aerobic Exercise and Task Repetition on the Neural Correlates of Executive Function in Young and Older Adults: A Crossover fMRI Study.
This randomized crossover study investigated the effects of acute aerobic exercise on brain activity during task switching in 17 young and 19 older adults.
Handgrip performance as a predictor of incident cognitive decline in older adults: A systematic review and meta-analysis.
This systematic review and meta-analysis examined the relationship between handgrip performance and cognitive decline in older adults aged 45 and above.
The effects of acute ketone monoester supplementation on brain insulin responsiveness and cognitive performance: Results of a randomized, double-blind, placebo-controlled crossover trial in older men with overweight.
This randomized, double-blind, placebo-controlled crossover trial examined the effects of acute ketone monoester (KME) supplementation on brain insulin responsiveness and cognitive performance in 18 older men with…
Insomnia and inflammatory exposure impair spatial memory and cognitive mapping in older adults: a randomized controlled trial.
This randomized controlled trial investigated the impact of insomnia and inflammatory exposure on spatial memory and cognitive mapping in 84 older adults aged 60-80.
Prevalence of osteosarcopenia in postmenopausal women: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed the prevalence of osteosarcopenia (OSP) in postmenopausal women, analyzing data from 16 studies involving 7,631 participants.
Effect of a digital mindfulness intervention for mild-to-moderate late-life depression: A randomized controlled trial.
This randomized controlled trial evaluated the FocusZen Mindfulness Stress Reduction System in 54 older adults with mild-to-moderate late-life depression (LLD).
Body mass index and baricitinib treatment effect in hospitalized adults with COVID-19: A secondary analysis of ACTT-2.
This secondary analysis of the ACTT-2 randomized controlled trial evaluated the impact of body mass index (BMI) on the efficacy of baricitinib in hospitalized COVID-19 patients.
User engagement with digital health technologies among older adults with cancer: A systematic review and qualitative evidence synthesis.
This systematic review synthesized qualitative evidence on user engagement with digital health technologies among older adults with cancer.
Economic Evaluation of Self-Administered Dual-Task Training Reducing Falls in Community-Dwelling Older Adults: Cost-Effectiveness Analysis of a Multicenter Randomized Control Trial.
This multicenter randomized controlled trial evaluated the cost-effectiveness of self-administered dual-task training (sDT) versus single-task training (sST) in preventing falls among 216 community-dwelling older adults…
Androgen therapy and musculoskeletal health in older adults: An umbrella review.
This umbrella review synthesized evidence from 11 systematic reviews and meta-analyses of randomized clinical trials assessing androgen therapy in older adults (≥60 years).
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