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2000 articles
October 202624
N-acetylcysteine mouthwash for prevention of oral mucositis in hematopoietic cell transplant recipients: a double-blind randomized controlled trial.
This double-blind randomized controlled trial evaluated the efficacy of N-acetylcysteine (NAC) mouthwash in preventing oral mucositis (OM) in 106 hematopoietic cell transplant (HCT) recipients.
Repeated remimazolam sedation for interstitial brachytherapy in cervical cancer: a randomized controlled trial.
This randomized controlled trial evaluated the safety and efficacy of repeated remimazolam sedation compared to propofol in 100 patients with cervical cancer undergoing interstitial brachytherapy.
Boesenbergia rotunda extract-based mucoadhesive mouth gargle for chemoradiation-induced oral mucositis: A prospective randomized controlled study.
This randomized controlled trial evaluated the efficacy of a Boesenbergia rotunda extract-based mouth gargle in managing chemoradiation-induced oral mucositis in head and neck cancer patients.
Effects of exercise and educational programs on long-term quality of life, anxiety, and depression in breast cancer survivors: an exploratory secondary analysis of the Setouchi breast project-10 randomized controlled trial.
This exploratory secondary analysis of a randomized controlled trial examined exercise and education for 342 patients with stage 0–III breast cancer within one year of completing treatment.
Prevalence of osteoporosis and low bone mass in men with prostate cancer: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the prevalence of osteoporosis and low bone mass in 91,913 men with prostate cancer (PCa).
Complete Regression of 11 Hepatic Metastases in Metastatic Pancreatic Adenosquamous Carcinoma and the Role of GPT in Patient Navigation.
A 65-year-old man with resected pancreatic adenosquamous carcinoma (pT3 pN2, R0) had 11 liver lesions interpreted as metastases on MRI.
Trial-specific absolute disease-free survival effects of postoperative PD-1/PD-L1 blockade after complete resection of NSCLC: A systematic review.
This systematic review estimated absolute disease-free survival (DFS) effects of postoperative single-agent PD-1/PD-L1 blockade after complete resection of non-small-cell lung cancer.
Continuous infusion of granulocyte colony-stimulating factor is associated with an advantage in neutrophil recovery in pediatric oncologic disorders.
This randomized controlled trial evaluated the effects of continuous infusion versus injection of granulocyte colony-stimulating factor (G-CSF) on neutrophil recovery in 20 pediatric oncology patients.
The impact of intratumor heterogeneity on outcome and resistance to therapy in primary breast cancer: a systematic review.
This systematic review examines the impact of intratumor heterogeneity (ITH) on chemotherapy resistance in primary breast cancer, analyzing 12 studies across various tumor subtypes.
Rapid manufactured CAR-T cells enriched for CD45RA-negative T cells exhibit superior persistence compared to conventional CAR-T therapy.
This comparative study evaluated InstanCAR-T, a rapid CD19 CAR-T manufacturing protocol enriched for CD45RA-negative T cells, against conventional CAR-T in laboratory assays, murine B-ALL models, and a Phase I clinical…
MRD negativity by PBMCs and ctDNA confirms deep and durable responses after epcoritamab monotherapy in R/R FL.
The EPCORE NHL-1 trial evaluated the efficacy of epcoritamab, a CD3 × CD20 bispecific antibody, in patients with relapsed/refractory follicular lymphoma (FL) after at least two prior therapies.
Narrative nursing for prolonged myelosuppression after autologous stem cell transplantation in multiple myeloma: A case report.
A 46-year-old man with multiple myeloma was admitted 7 months post-autologous stem cell transplantation due to febrile neutropenia and erosive oral mucosal lesions.
Primary pulmonary mucosa-associated lymphoid tissue lymphoma presenting as a right hilar mass: A case report.
A 44-year-old male presented with an incidental right hilar mass discovered during routine screening. He was asymptomatic, and imaging revealed a 3.9 × 3.5 cm mass causing bronchial compression and post-obstructive…
Regional practice differences significantly affect the benefit of post-HCT gilteritinib in FLT3-ITD AML.
The phase 3 MORPHO trial evaluated the efficacy of gilteritinib versus placebo in post-hematopoietic cell transplantation (HCT) for FLT3-ITD AML patients.
Hypofractionated 44 Gy in 20 fractions versus conventional chemoradiation in cervical cancer: 2-year results of the randomized HYPOCx-iRex trial with an exploratory pooled analysis of a single-institute EMBRACE-II cohort.
The randomized HYPOCx-iRex trial compared hypofractionated chemoradiation (44 Gy in 20 fractions) with conventional chemoradiation (45 Gy in 25 fractions) for locally advanced cervical cancer; an exploratory pooled…
Tumor-Free Circulating Tumor DNA in Node-Negative Rectal Cancers Undergoing Neoadjuvant Chemotherapy, Excision, and Observation in the Phase II NEO Trial (CO.28).
The Phase II NEO trial investigated the role of circulating tumor DNA (ctDNA) in guiding treatment decisions for 53 patients with node-negative rectal cancer undergoing neoadjuvant chemotherapy and transanal excision.
Genetic evidence for associations between gastroesophageal reflux disease and site-specific extraesophageal cancers: A Mendelian randomization study.
This Mendelian randomization study investigated the relationship between genetically predicted gastroesophageal reflux disease (GERD) and 22 extraesophageal cancers using data from over 600,000 individuals.
Concurrent presentation of distinct extranodal and splenic marginal zone lymphomas.
A patient was diagnosed with both extranodal marginal zone lymphoma (EMZL) of the ocular adnexa and splenic marginal zone lymphoma (SMZL).
Angioimmunoblastic T-cell lymphoma with secondary hemophagocytic lymphohistiocytosis initially misdiagnosed as classical Hodgkin lymphoma: A case report.
A 72-year-old man presented with fatigue, recurrent fever, severe pancytopenia, and splenomegaly, initially diagnosed with Hodgkin lymphoma.
Type II RAF Inhibitor Tovorafenib in Recurrent/Refractory Melanoma or Other Solid Tumors With BRAF Fusions or CRAF/RAF1 Fusions or Amplification: Phase II FIRELIGHT-1 Substudy.
This Phase II clinical trial evaluated the efficacy and safety of tovorafenib in 23 patients with recurrent/refractory solid tumors harboring BRAF or CRAF fusions/amplifications.
Comparisons in Analgesic Effects Between Ultrasound-Guided Erector Spinae Plane Block and Ultrasound-Guided Modified Intercostal Nerve Block in Modified Radical Mastectomy: A Randomized Controlled Trial.
Postoperative acute pain is a common challenge after breast cancer surgery. This randomized controlled trial compared the analgesic effects of ultrasound-guided erector spinae plane block (ESPB) and modified intercostal…
Recurrent giant retroperitoneal liposarcoma: A case report.
A 48-year-old male with a 13-year history of recurrent myxoid liposarcoma presented with significant abdominal distension due to a massive abdominopelvic mass measuring 352 mm.
Analysis of quality-adjusted time without symptoms or toxicity (Q-TWiST) in patients with metastatic hormone-sensitive prostate cancer from the ARASENS trial.
This Q-TWiST analysis of the multicenter, randomized ARASENS trial evaluated quality-adjusted survival in patients with metastatic hormone-sensitive prostate cancer receiving darolutamide plus androgen deprivation…
Intraoperative Dexmedetomidine and Postoperative Delirium After Head and Neck Cancer Surgery with Free-Flap Reconstruction: A Secondary Analysis of a Randomized Placebo-Controlled Trial.
This delirium-focused secondary analysis of a single-centre, randomized, double-blind, placebo-controlled trial examined adults undergoing elective head and neck cancer surgery with free-flap reconstruction.
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