Trending archive
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464 articles
June 20263
Incidence and risk factors of sepsis-associated delirium in the intensive care unit: a systematic review and meta-analysis.
This systematic review and meta-analysis examined the incidence and risk factors of sepsis-associated delirium (SAD) in ICU patients, analyzing data from 52 studies with 89,789 patients.
Obexelimab for the Treatment of IgG4-Related Disease.
This phase 3 randomized controlled trial evaluated obexelimab in 194 patients with active IgG4-related disease. The study found that obexelimab significantly prolonged the time to the first disease flare requiring…
Clinical Instruments Assessing Harms and Benefits of Long-Term Opioid Therapy for Chronic Pain: A Scoping Review.
This scoping review examined clinical instruments assessing harms and benefits of long-term opioid therapy (LTOT) in adults with chronic non-cancer pain.
May 202621
12‑weeks fisetin supplementation and interval resistance with aerobic training: changes in Maresin‑1 and inflammatory markers in men with obesity: a randomized controlled trial.
This randomized controlled trial investigated the effects of fisetin supplementation combined with interval resistance and aerobic training on inflammatory markers and insulin resistance in 44 obese men.
Evaluation of a pantoprazole and 4-desmethylpantoprazole-sulfate metabolic ratio as a novel CYP2C19 phenotyping method.
This randomized controlled trial evaluated pantoprazole as a novel phenotyping method for CYP2C19 in 20 healthy participants.
Inflammatory Pseudotumor Due to Actinomycosis Simulating Post-Transplant Lymphoproliferative Disorder.
A female liver transplant recipient presented with a hepatic collection after experiencing biliary complications. Imaging suggested a possible abscess, but the clinical response to initial treatment was poor, raising…
Optimizing Initial Dosing for Tacrolimus and Mycophenolate in Living Donor Liver Transplantation: A Systematic Critical Review.
This systematic review evaluated the pharmacokinetics of tacrolimus and mycophenolate in living donor liver transplantation (LDLT) recipients.
Vegan versus traditional Mediterranean diet effects on cardiometabolic outcomes in women with fibromyalgia:FIBROVEG study.
The FIBROVEG study, a randomized controlled trial, assessed the effects of a vegan Mediterranean diet (VegMedDiet) versus a traditional Mediterranean diet (MedDiet) on cardiometabolic outcomes in 22 women with…
A systematic review of qualitative research on HIV and food insecurity in high-income countries.
This systematic review synthesized qualitative research on food insecurity among people living with HIV in high-income countries, focusing on studies from the US and Canada.
Advancing stroke prevention in atrial fibrillation: a systematic review of machine learning-based risk prediction models.
This systematic review evaluated machine learning (ML) models for predicting ischemic stroke in patients with atrial fibrillation (AF) using electronic health record data.
Fan Therapy for Alleviating Dyspnea in Adults: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the effectiveness of fan therapy for alleviating dyspnea in adults, analyzing 15 studies with 623 participants.
Effect of urinary catheter securement band on meatal pressure injury in male intensive care patients: A randomized controlled trial.
This randomized controlled trial evaluated the effectiveness of a urinary catheter securement band in preventing meatal pressure injury (meatal-PI) among 248 male ICU patients.
Interventions that strengthen the patient-clinician relationship improve healthcare outcomes: An updated systematic review and meta-analysis.
This systematic review and meta-analysis evaluated clinician-focused interventions aimed at strengthening patient-clinician relationships across 28 randomized controlled trials involving 18,046 patients.
Phosphate enemas causing profound refractory hypocalcaemia: A case report.
A 37-year-old woman with alcohol-related liver disease was admitted with melaena and coffee-ground vomiting and developed severe hepatic encephalopathy.
Adverse Gastrointestinal Effects of Alendronate Versus Risedronate in Osteoporosis: A Systematic Review and Meta-analysis.
This systematic review and meta-analysis compared gastrointestinal (GI) adverse effects of alendronate and risedronate in osteoporosis treatment, analyzing data from six randomized controlled trials involving 4,151…
Fever, lymphadenopathy, and a diagnostic dilemma: a case of Kikuchi-Fujimoto disease masquerading as tuberculosis in a diabetic patient.
A middle-aged man with diabetes from South India presented with prolonged fever, substantial weight loss, and generalized lymphadenopathy.
Assessing the Safety and Probiotic Potential of Bifidobacterium longum subsp. infantis BI45: A Comprehensive Study from Genomic Analysis to Randomized Controlled Clinical Trial in Healthy Adults.
This randomized controlled trial assessed the safety and efficacy of Bifidobacterium longum subsp. infantis BI45 in 48 healthy adults.
Sex-related disparities in sepsis in western Europe: A systematic review and meta-analysis.
This systematic review and meta-analysis examined sex-stratified mortality and infection patterns among adults with sepsis in Western Europe. It included 18 studies with 671,861 participants.
Safety, pharmacokinetics and pharmacodynamics of NXC736, a novel sphingosine-1-phosphate receptor modulator.
This randomized controlled trial evaluated the safety, pharmacokinetics, and pharmacodynamics of NXC736, a novel sphingosine-1-phosphate receptor modulator, in healthy male participants.
A Phase 1 Study Evaluating the Pharmacokinetics, Pharmacodynamics, and Safety of Zerlasiran in Japanese Participants.
This Phase 1 open-label trial evaluated the pharmacokinetics, pharmacodynamics, and safety of zerlasiran in 18 Japanese adults with elevated lipoprotein(a).
Early vasopressin administration in septic shock: A systematic review, meta-analysis, and multicenter retrospective observational study.
This study evaluated the timing of vasopressin initiation in septic shock through a multicenter registry analysis and a systematic review with meta-analysis.
Randomized Sham-Controlled Trial of Translumbosacral Neuromodulation Therapy for Fecal Incontinence.
This multicenter, double-blind, randomized sham-controlled trial evaluated the efficacy and safety of translumbosacral neuromodulation therapy (TNT) in patients with fecal incontinence (FI).
Effect of nipocalimab on IgG responses to vaccinations and viral infections in patients with IgG autoantibody-mediated diseases: Post hoc analyses of three randomized, placebo-controlled trials.
This study evaluated the effects of nipocalimab on IgG responses to vaccinations and viral infections in patients with IgG autoantibody-mediated diseases, using post hoc analyses from three randomized…
Identifying DASH Adherence Patterns and Their Association With Dietary Behaviors Among Adults With Hypertension.
This randomized controlled trial analyzed DASH diet adherence patterns among 301 adults with hypertension. The study identified three adherence subgroups: low (44.2%), high (41.2%), and mixed-pattern (14.6%).
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