Trending archive

Every article that has appeared in Trending stays here. Search by title, journal, author or PMID, and narrow by date.

542 articles

July 20262

June 202622

Clinical ResearchGeriatricsOpen access

Effectiveness of community-based physical activity models in improving quality of life among elderly: A systematic review.

This systematic review evaluated the effectiveness of community-based physical activity models on quality of life in older adults (≥60 years).

Aten PrimariaJun 30, 2026Read summary
Clinical ResearchPsychiatry

Brexpiprazole With Antidepressants for Agitation in Alzheimer's Dementia: Post Hoc Analysis.

This post hoc analysis of two Phase 3 randomized controlled trials evaluated the efficacy and safety of brexpiprazole for agitation in Alzheimer's dementia, both with and without concomitant antidepressants.

Am J Geriatr PsychiatryJun 30, 2026Read summary
Clinical ResearchGeriatrics

Rehabilitation strategies in post menopausal women: a systematic review and meta-analysis of randomized trials.

This systematic review and meta-analysis evaluated the effects of rehabilitation and exercise-based interventions on postmenopausal women.

Eur J Obstet Gynecol Reprod BiolJun 29, 2026Read summary
Clinical ResearchGeriatrics

Diet and Cognitive Function in Aging: An Individual Participant Data Meta-Analysis from 8 Cohorts in Europe and the United States.

This meta-analysis examined the relationship between dietary patterns and cognitive function in 17,368 participants from 8 cohorts in Europe and the US.

J NutrJun 29, 2026Read summary
Clinical ResearchGeriatrics

Effects of different intensities of aerobic exercise on intestinal permeability and inflammatory response in older adults: Randomized clinical trial.

This randomized clinical trial examined the effects of high-intensity versus low-intensity aerobic exercise on intestinal permeability and inflammatory responses in 29 older adults (≥60 years).

Exp GerontolJun 29, 2026Read summary
Clinical ResearchGeriatrics

Gut microbial signature for frailty discrimination: a metagenomic meta-analysis of 28 independent cohorts.

This meta-analysis examined gut microbial signatures associated with frailty in 955 individuals from 28 cohorts across 24 countries.

Exp GerontolJun 29, 2026Read summary
Clinical ResearchGeriatricsOpen access

Study protocol for FAXAge: a randomized, controlled clinical trial of fasting and exercise to slow aging in humans.

The FAXAge study is a randomized controlled trial investigating the effects of fasting and exercise on biological aging in 240 healthy adults aged 65 and older.

GeroscienceJun 29, 2026Read summary
Clinical ResearchGeriatricsOpen access

Personalized blood flow restriction training at variable occlusion pressures improves multisystem function in overweight and obese older women.

This randomized controlled trial examined the effects of 12-week low-intensity blood flow restriction (BFR) training at varying arterial occlusion pressures on physiological functions in 180 overweight and obese women…

Eur J Appl PhysiolJun 29, 2026Read summary
Clinical ResearchGeriatrics

Multidomain Benefits of Exergaming for Sarcopenia Management in Institutionalized Older Adults: Physical, Psychological, and Social Outcomes.

This pragmatic quasi-experimental pre-post study with matched facility pairs assessed 12 weeks of Nintendo Switch Ring Fit Adventure in 72 institutionalized adults aged 65 years or older with sarcopenia at six Taiwanese…

Arch Phys Med RehabilJun 29, 2026Read summary
Clinical ResearchGeriatrics

Effectiveness of ecological momentary interventions for improving 24-hour movement behaviors in older adults: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the effectiveness of ecological momentary interventions on 24-hour movement behaviors in older adults.

Int J Nurs StudJun 28, 2026Read summary
Clinical ResearchGeriatrics

The benefit of physical exercise in improving quality of life, VO 2 max and sleep quality among older adults living with HIV: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the impact of physical exercise on quality of life, VO₂ max, and sleep quality in older adults living with HIV.

Geriatr NursJun 28, 2026Read summary
Clinical ResearchGeriatrics

Traditional nurse-led vs chatbot education for older adults in postoperative complication prevention after major visceral surgery: A randomized controlled trial.

This randomized controlled trial evaluated the effectiveness of chatbot-based education compared to traditional nurse-led education in 214 older adults undergoing major abdominal surgery.

Geriatr NursJun 28, 2026Read summary
Clinical ResearchPsychiatry

Measurement stability and differential domain-specific trajectories of the PHQ-9 in late-life depression: Evidence from a collaborative care trial.

This randomized controlled trial analyzed the stability of the two-factor structure of the PHQ-9 in older adults (N=558) with moderate-to-severe depression.

J Affect DisordJun 27, 2026Read summary
Clinical ResearchGeriatrics

Post-intervention effectiveness of a computerized personalized cognitive stimulation program adapted according to cognitive reserve in older adults without cognitive impairment in Primary Care: A randomized clinical trial.

This randomized clinical trial evaluated a computerized cognitive stimulation program tailored to cognitive reserve in 102 community-dwelling older adults without cognitive impairment.

Arch Gerontol GeriatrJun 27, 2026Read summary
Clinical ResearchGeriatrics

Association of vegetable and fruit intake with risk of dementia: 3 prospective studies and meta-analysis of cohort studies.

This meta-analysis examined the relationship between vegetable and fruit intake and dementia risk across three prospective cohorts, involving 18,339 participants aged ≥45 years.

Am J Clin NutrJun 27, 2026Read summary
Clinical ResearchCardiology

The co-existence of Ehlers-Danlos syndrome and postural orthostatic tachycardia syndrome: A systematic review of the literature.

This systematic review evaluated the co-existence of Ehlers-Danlos syndrome (EDS) and postural orthostatic tachycardia syndrome (POTS) across 30 studies involving 8421 EDS patients and 12,983 POTS patients.

Auton NeurosciJun 27, 2026Read summary
Clinical ResearchGeriatricsOpen access

Effects of Concurrent Strength and Aerobic Exercise Training on Cognitive Health in Adults With Physiological or Neurocognitive Disorders: Systematic Review With Meta-analysis of Randomized Controlled Trials.

This systematic review and meta-analysis of randomized controlled trials assessed concurrent strength and aerobic exercise training (CET) and global cognition in middle-aged and older adults with physiological or…

Sports HealthJun 25, 2026Read summary
Clinical ResearchOrthopedic Surgery

Malnutrition and adverse outcomes after spine surgery: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the impact of preoperative malnutrition on postoperative outcomes in spine surgery patients.

Spine JJun 24, 2026Read summary
Clinical ResearchCardiology

Clinical outcomes after catheter ablation for atrial fibrillation in elderly patients: a meta-analysis with time-to-event data reconstruction.

This systematic review and meta-analysis compared long-term outcomes after catheter ablation for atrial fibrillation in elderly and non-elderly patients, drawing on 28 studies involving 22,921 patients.

J Interv Card ElectrophysiolJun 24, 2026Read summary
Clinical ResearchGeriatrics

Role of an Ayurvedic formulation 'Kalyanaka Ghrita' in mild cognitive impairment: A single-patient, quasi-randomized, controlled, open-label N-of-1 trial.

To assess the efficacy and safety of Kalyanaka Ghrita in a patient diagnosed with Mild Cognitive Impairment (MCI) using an N-of-1 trial design.

J EthnopharmacolJun 23, 2026Read summary
Clinical ResearchNeurology

Effects of traditional Chinese exercises on sleep quality among post-stroke survivors: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the effects of traditional Chinese exercises (TCEs) on sleep quality, anxiety, and depression in post-stroke survivors.

Complement Ther MedJun 23, 2026Read summary
Clinical ResearchPsychiatry

Prevalence of Sarcopenia-Related Muscle-Health Phenotypes in Patients With Severe Mental Illness: A Systematic Review and Meta-Analysis.

This systematic review and random-effects meta-analysis assessed the prevalence of sarcopenia-related muscle-health phenotypes in people with severe mental illness (SMI).

Am J Geriatr PsychiatryJun 22, 2026Read summary

Stay updated for free

Get the 3 most interesting publications in one specialty each week.

Weekly email. Unsubscribe anytime.

Want this personalized?

Stop searching the literature. Choose what you follow and xxcode will build your personalized medical digest.

  • Your specialties
  • Your filters and thresholds
  • Clinical Research + Case Reports, tuned separately
  • Automatic weekly delivery
  • Audio and text

Prefer listening? Personalized audio digests are available with Pro.