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937 articles
September 202617
Five-year efficacy and safety of guselkumab for moderately to severely active Crohn's disease: Results from the phase 2 GALAXI 1 trial.
The phase 2 GALAXI 1 trial assessed the long-term efficacy and safety of guselkumab in patients with moderately to severely active Crohn's disease.
Endoscopic Ultrasound-Guided Transluminal Drainage of Walled-Off Necrosis Using Naso-Cystic Drain With Metal Stent Versus Metal Stent Alone: A Randomized Controlled Pilot Study.
This randomized controlled pilot study evaluated the efficacy of endoscopic ultrasound-guided drainage with nasocystic drainage (NCD) versus without NCD in 40 patients with symptomatic walled-off necrosis (WON).
Incidence and predictors of surgical recurrence after primary ileocolic resection in Crohn ileitis: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the incidence and predictors of surgical recurrence after primary ileocolic resection (ICR) in patients with Crohn disease.
The prevalence of abdominal computed tomography imaging findings in patients with inflammatory bowel disease who present to the emergency department: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the prevalence of abdominal CT imaging findings in patients with inflammatory bowel disease (IBD) presenting to the emergency department.
Incidence of acne in patients with inflammatory bowel disease treated with Janus kinase inhibitors: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the incidence of acne in 9902 patients with inflammatory bowel disease (IBD) treated with Janus kinase (JAK) inhibitors.
The Great Imitator: Syphilitic Hepatitis Presenting as a Mimic to Autoimmune Liver Disease.
A 34-year-old male on PrEP for HIV presented with epigastric pain and constitutional symptoms. Laboratory tests showed elevated liver enzymes and positive smooth muscle antibodies, suggesting autoimmune hepatitis.
Acute Effects of Non-Oil-Seed Pulses on Parameters of Cardiometabolic Health: A Systematic Review of Human Intervention Studies.
This systematic review evaluated the acute effects of non-oil-seed pulses on cardiometabolic health parameters in humans. It found that 28 of 40 studies reported lower glucose responses and 16 of 24 studies reported…
Proficiency in Esophageal Peroral Endoscopic Myotomy: A Meta-Analysis of Learning Curves.
This meta-analysis evaluated the learning curve of peroral endoscopic myotomy (POEM) across 3197 procedures. It found that proficiency in procedure speed was achieved during the 20-40 phase of learning, with mean…
Performance, Efficacy, and Safety of Lubiprostone in Bowel Preparation Regimens: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
This systematic review and meta-analysis evaluated the efficacy and safety of lubiprostone as an adjunct to bowel preparation for colonoscopy in 1322 patients across eight randomized controlled trials.
Effects of Acute Low- and Moderate-Dose Alcohol on Chronic Disease-Related Biomarkers in Healthy Light and Heavy Drinkers.
This randomized controlled trial examined the effects of low-dose (0.35 g/kg) and moderate-dose (0.60 g/kg) alcohol on disease-related biomarkers in 32 healthy adults, both light and heavy drinkers.
Immune Checkpoint Inhibitor-Induced Pancreatitis.
A case report described five female patients who developed immune checkpoint inhibitor-induced pancreatitis (ICIPI) after receiving combination ICI therapy.
Effect of Age and Age-Defined Menopausal Status on Linaclotide Efficacy and Safety in Adults With Irritable Bowel Syndrome With Constipation or Chronic Idiopathic Constipation: Post Hoc Analyses of Phase 2b/3 Studies.
This post hoc analysis of eight randomized, placebo-controlled trials evaluated linaclotide's efficacy and safety in adults with irritable bowel syndrome with constipation (IBS-C) or chronic idiopathic constipation…
Impact of evidence-based feeding protocols on clinical outcomes and nutritional delivery in critically ill adults: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the impact of evidence-based feeding protocols on clinical outcomes and nutritional delivery in critically ill adults.
Systematic review and meta-analysis on key controversies in the management of diverticular disease: a multi-society collaboration.
This systematic review and meta-analysis evaluated the management of diverticular disease, focusing on symptomatic uncomplicated diverticular disease (SUDD), uncomplicated diverticulitis, and complicated diverticulitis.
Efficacy of double-balloon enteroscopy-endoscopic retrograde cholangiopancreatography for hepaticojejunostomy strictures: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the efficacy of double-balloon enteroscopy-assisted endoscopic retrograde cholangiopancreatography (DBE-ERCP) for managing hepaticojejunostomy anastomotic strictures…
Dietary Soybean vs. Palm Oils Differ in Effects on Liver Fat in Adults With MAFLD: A 16-Week, Double-Masked, Randomized Controlled Trial.
This 16-week, double-masked randomized controlled trial compared soybean oil, rich in linoleic acid, with palm oil in adults with metabolic dysfunction-associated fatty liver disease (MAFLD).
Protein-fermentation biomarkers in plasma and urine differ between bovine plasma protein and whey protein isolate in a randomized fully controlled dietary intervention.
This randomized, controlled crossover dietary intervention compared bovine plasma protein (BPP) with whey protein isolate (WPI) in 15 healthy adults.
August 20267
Effect of Lidocaine Spray on the Sedative Dose of Remimazolam During Gastroscopy in Adults: A Prospective, Randomized Dose-Response Trial Using an Up-Down Sequential Allocation Method.
To investigate the effect of oropharyngeal topical lidocaine spray on the sedative dose of remimazolam required for gastroscopy in adults.
Videolaparoscopic pancreatojejunostomy using a hybrid technique in chronic pancreatitis without significant ductal dilatation.
A 52-year-old man with alcoholic chronic pancreatitis presented with severe abdominal pain requiring opioids. Imaging revealed a mildly dilated pancreatic duct with segmental strictures and a peripancreatic cyst.
Proton pump inhibitors in invasively ventilated patients with SARS-CoV-2: a substudy of the re-evaluating the inhibition of stress erosions trial.
This substudy of the REVISE trial evaluated the effects of pantoprazole in 532 mechanically ventilated patients with SARS-CoV-2.
Robotic-assisted endoscopic submucosal dissection for superficial gastrointestinal neoplasms: a bayesian meta-analysis & systematic review.
This systematic review and Bayesian meta-analysis evaluated the efficacy and safety of robotic-assisted endoscopic submucosal dissection (R-ESD) for superficial gastrointestinal neoplasms, analyzing data from five…
Mediterranean diet and metabolic outcomes in nafld/masld: A systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis evaluated the effects of the Mediterranean diet on metabolic outcomes in patients with non-alcoholic fatty liver disease (NAFLD) or metabolic dysfunction associated steatotic…
Effect of sucrose-free brazzein-sweetened ice cream on continuously monitored glycemic response in patients with metabolic dysfunction-associated steatotic liver disease: A randomized controlled double-blind crossover trial.
This randomized controlled trial evaluated the glycemic response to ice cream sweetened with brazzein, a natural sweet protein, in 101 adults with metabolic dysfunction-associated steatotic liver disease (MASLD).
SAGES clinical practice guidelines for the management of symptomatic walled-off pancreatic necrosis.
This systematic review developed clinical practice guidelines for managing symptomatic walled-off pancreatic necrosis (WOPN) in adults.
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