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412 articles
March 202617
Improving Patient Comfort of Vibratory Anesthetic Devices With a Dampener: A Pilot Study.
This single-site, participant-blinded randomized pilot study assessed whether a cotton buffer that dampens vibratory anesthetic device (VAD) vibration improves comfort in adults receiving applications at five anatomical…
Comparative efficacy of intralesional therapies for keloid scars: a network meta-analysis.
This network meta-analysis compared the efficacy and safety of intralesional treatments for keloid scars, drawing on randomized, non-randomized, and crossover trials.
Itchy, blistering rash in pregnancy: pemphigoid gestationis.
A woman in her 30s developed an intensely itchy blistering eruption one day after delivery. Routine histopathology was nondiagnostic, but direct immunofluorescence showed linear complement deposition along the basement…
Psychoeducational schema therapy for psoriasis and atopic dermatitis: a randomized controlled pilot crossover trial.
This randomized pilot crossover trial tested a brief psychoeducational schema-therapy intervention in dermatology outpatients with psoriasis or atopic dermatitis and a PHQ-2 score ≥ 3.
A rare case of migrating dermal filler mimicking lymphadenopathy.
A 30-year-old man presented with bilateral submandibular nodules. MRI showed bilateral masses, while sonography suggested cysts or lymph nodes.
'Oral isotretinoin plus desloratadine for acne vulgaris: an updated global meta-analysis of efficacy, safety, and patient-centered outcomes'.
This systematic review and meta-analysis assessed oral isotretinoin plus desloratadine versus isotretinoin alone for acne vulgaris, pooling nine clinical trials involving 608 patients.
JAK inhibition therapy for intractable cutaneous infectious granulomatosis with unknown etiology: a case report.
A 36-year-old woman presented with chronic, treatment-resistant plaques on her face and legs. Histopathology supported infectious granulomatosis, but no specific pathogen was identified, including after antifungal…
Lebrikizumab off-therapy remission sustained up to 38 weeks in atopic dermatitis.
This pooled subgroup analysis of two randomized, double-blind, placebo-controlled phase 3 trials examined serum lebrikizumab levels and sustained response after treatment withdrawal in adults and adolescents with…
Raising the bar of efficacy in Atopic Dermatitis: deep response in week 16 responders treated with lebrikizumab over 2 years.
This analysis followed patients with moderate-to-severe atopic dermatitis who responded to lebrikizumab by Week 16 in the ADvocate1&2 randomized trials and continued into the ADjoin extension.
Treatment of discoid lupus erythematosus with crisaborole.
A 20-year-old woman had a persistent erythematous nasal plaque for seven years that had been misdiagnosed and had not responded to multiple systemic and topical treatments, including antimalarials.
Dupilumab subgroup responder analysis: a post hoc analysis from LIBERTY PRIME and PRIME2 in prurigo nodularis.
This post hoc subgroup analysis pooled data from the randomized PRIME and PRIME2 trials, which enrolled 311 adults with prurigo nodularis and compared dupilumab 300 mg every 2 weeks with matching placebo for 24 weeks.
Bimekizumab efficacy in scalp, nail and palmoplantar psoriasis versus comparators and over 4 years.
This analysis pooled data from four phase 3/3b randomized trials and an open-label extension to assess bimekizumab for scalp, nail, and palmoplantar psoriasis in adults with moderate to severe plaque psoriasis and…
Comparison of long-term efficacy and safety of different therapeutic approaches for vulvar Lichen sclerosus: a systematic review and meta-analysis.
This systematic review and meta-analysis compared laser and photodynamic therapy (PDT) with topical glucocorticoids for vulvar lichen sclerosus.
Systematic Review and Meta-Analysis of Allergic Contact Dermatitis from 2-Octyl Cyanoacrylate Adhesives.
This systematic review and meta-analysis examined allergic contact dermatitis (ACD) associated with 2-octyl cyanoacrylate adhesives used for surgical wound closure.
Efficacy and safety of topical 3% minoxidil for facial hair enhancement in transmen: a randomized, double-blind, placebo-controlled trial.
This randomized, double-blind, placebo-controlled trial assessed topical 3% minoxidil for facial hair enhancement in 69 transgender men receiving stable gender-affirming hormone therapy.
Treatment of redness in rosacea with potassium-titanyl-phosphate (KTP) 532 nm laser with and without topical 1% ivermectin cream: a randomized split-face trial.
This randomized, evaluator-blinded split-face trial assessed whether topical ivermectin adds benefit to KTP 532 nm laser treatment for rosacea.
Injectable platelet-rich fibrin as a valid therapeutic option for inactive linear morphea (en coup de saber): report of cases.
Two patients with inactive linear morphea in an en coup de saber pattern had band-like, atrophic lesions affecting the frontoparietal area, with facial contour defects and pigmentation.
February 20267
Randomized dose-finding study of anti-KIT barzolvolimab in patients with chronic spontaneous urticaria.
This phase 2, multicenter, double-blind, placebo-controlled randomized trial assessed barzolvolimab, an anti-KIT antibody that depletes mast cells, in adults with antihistamine-refractory chronic spontaneous urticaria…
A Rare Presentation of Congenital Melanocytic Nevus on the Tongue and Lower Lip Mucosa.
A 36-year-old man had asymptomatic pigmented lesions present since childhood on the dorsal tongue and lower-lip mucosa. Examination showed hyperpigmented tongue patches and discrete lower-lip macules.
Acute Muscle Injury and Subcutaneous Edema in a Patient with Anti-nuclear Matrix Protein-2 Antibody Positive Dermatomyositis Sine Dermatitis.
A patient with anti-NXP-2 antibody-positive dermatomyositis sine dermatitis presented with acute muscle injury and marked creatine kinase elevation, without a skin rash.
Predictors of Efficacy Maintenance After Vunakizumab Discontinuation in Patients With Moderate-to-Severe Plaque Psoriasis: A Post Hoc Analysis of a Randomized Controlled Trial.
This post hoc analysis of a phase III randomized controlled trial examined predictors of maintained response after vunakizumab discontinuation in 291 patients with moderate-to-severe plaque psoriasis who had achieved…
Biologic Treatments in Adolescents With Moderate-to-Severe Atopic Dermatitis: A Systematic Literature Review and Network Meta-analysis.
This systematic literature review and Bayesian network meta-analysis compared biologic therapies for adolescents aged 12 to 17 with moderate-to-severe atopic dermatitis.
Midface volumization and skin quality enhancement with a hyaluronic acid-polynucleotide hybrid filler: a 24-week prospective open-label study.
This single-center, prospective, open-label clinical trial evaluated a hyaluronic acid–polynucleotide hybrid filler in 15 adults with moderate-to-severe anteromedial cheek volume loss.
Pembrolizumab-associated exacerbation of lichen planopilaris in a patient with metastatic melanoma.
A 75-year-old woman with stable, biopsy-proven lichen planopilaris (LPP) developed reactivation after ten cycles of pembrolizumab for stage IIC melanoma.
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