Trending archive
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464 articles
July 20263
Remimazolam Versus Midazolam for Sedation in Mechanically Ventilated Patients with Severe Pneumonia: A Randomized Controlled Trial.
This single-center, prospective randomized controlled trial compared remimazolam with midazolam for sedation in 68 adults with severe pneumonia receiving invasive mechanical ventilation.
Intravenous iron administration and management of adverse events: a systematic review and Network for the Advancement of Patient Blood Management, Haemostasis and Thrombosis consensus recommendations.
This systematic review by the NATA provides consensus recommendations on the safety of intravenous iron therapy for iron deficiency and iron-deficiency anemia.
Treatment and management approaches for ketamine misuse: A systematic review of medical interventions.
Ketamine, initially developed as an anesthetic and now increasingly prescribed for treatment-resistant depression, is also widely misused in recreational contexts.
June 202621
Mediterranean versus Western diet: Effects on gut microbiota, systemic inflammation, and clinical implications in metabolic health.
This systematic review examined the effects of the Mediterranean and Western diets on gut microbiota and systemic inflammation.
Timing It Right theory-based staged video education for patients on home enteral nutrition: A randomized controlled trial.
This randomized controlled trial evaluated the effectiveness of Timing It Right (TIR)-based staged video education for 100 patients on home enteral nutrition (HEN).
Dengue epidemic in Northern Peru (2024): analysis of 2,449 cases.
During the 2024 dengue epidemic in northern Peru, a retrospective analysis of 2,449 confirmed cases revealed that 54.4% had dengue without warning signs, 45.0% had dengue with warning signs, and 0.7% had severe dengue.
The co-existence of Ehlers-Danlos syndrome and postural orthostatic tachycardia syndrome: A systematic review of the literature.
This systematic review evaluated the co-existence of Ehlers-Danlos syndrome (EDS) and postural orthostatic tachycardia syndrome (POTS) across 30 studies involving 8421 EDS patients and 12,983 POTS patients.
Balanced crystalloids versus saline and mortality in hospitalized patients: a hierarchical Bayesian meta-analysis of cluster-randomized trials.
This hierarchical Bayesian meta-analysis evaluated the effectiveness of balanced crystalloids versus saline in hospitalized patients across six cluster-randomized trials involving 42,223 patients.
Phentermine/Topiramate in Obese, Diabetic Uric Acid Stone Formers: An Open-Label Randomized Feasibility Trial.
This open-label randomized feasibility trial evaluated the effects of phentermine/topiramate on uric acid kidney stone burden in obese, diabetic patients.
Vitamin B12 Deficiency in Sickle Cell Disease: Method-Driven Estimates and Systematic Diagnostic Misclassification.
This systematic review assessed the prevalence of vitamin B12 deficiency in sickle cell disease (SCD) across 14 observational studies.
Does consuming ascorbate-rich fruits and fruit juices with meals improve iron bioavailability? A systematic review and meta-analysis of interventions.
This systematic review and meta-analysis evaluated the impact of ascorbate-rich fruits on iron bioavailability in females and children.
Pacing spikes without visible QRS complexes: Failure to capture?
A man in his 60s with advanced infra-Hisian conduction disease received a dual-chamber pacemaker with left bundle branch area pacing.
Assessment of in-hospital mortality in patients with upper gastrointestinal bleeding on antithrombotic treatment.
This systematic review and meta-analysis evaluated the impact of antithrombotic therapy on in-hospital mortality in patients with upper gastrointestinal bleeding.
Ultrasound for the determination of appropriate needle length for intragluteal injection of long-acting rilpivirine-cabotegravir.
Two patients on long-acting cabotegravir and rilpivirine experienced virological rebound. The first, an obese individual, had ultrasound findings of significant subcutaneous adipose tissue and injection granulomas…
Machine learning vs. traditional methods for predicting postoperative cardiac complications after non-cardiac surgery: a systematic review and Bayesian network meta-analysis.
This systematic review and Bayesian network meta-analysis evaluated the predictive performance of machine learning models versus traditional risk scores for postoperative cardiac complications in non-cardiac surgery.
Collaborative care intervention for risky opioid use among primary care patients: The STOP randomized clinical trial.
The STOP randomized controlled trial evaluated a collaborative care intervention aimed at reducing risky opioid use among primary care patients. Conducted across five U.S.
Effects of Different Training Modalities on Circulating Irisin Levels in Overweight and Obesity Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
This systematic review and meta-analysis evaluated the effects of various exercise modalities on circulating irisin levels in overweight and obese adults.
Pharmacometabolomics of treatment response to antihypertensive drugs: a systematic review.
This systematic review examined the role of pharmacometabolomics in predicting responses to antihypertensive drugs in patients with primary hypertension.
Unintentional fatal overdose of veterinary levamisole in a human subject.
A patient presented with nausea, vomiting, tremors, and visual changes after an oral ingestion of levamisole, leading to bradycardia and pulseless electrical activity cardiac arrest.
Dynamic regulation of circulating endotrophin by changes in fat mass in humans.
This randomized controlled trial investigated the relationship between short-term changes in fat mass and circulating endotrophin levels in 73 healthy adults.
Longitudinal effects of antiretroviral therapy on the oral microbiota in people living with HIV: A systematic review.
This systematic review assessed longitudinal changes in oral microbiota before and after antiretroviral therapy (ART) initiation in people living with HIV.
Lowering salivary pH with sugar-containing gum augments salivary nitrite production and blood pressure reduction with dietary nitrate (beetroot juice).
This randomized controlled trial investigated the effects of sugar-containing gum on salivary pH and its subsequent impact on salivary nitrite production and blood pressure in 14 healthy volunteers.
Rare case of bacteremia, liver abscess and possible infective endocarditis caused by Fusobacterium nucleatum.
A 75-year-old man with type 2 diabetes presented with high fever, rigors, and hemodynamic instability; examination revealed a new systolic murmur.
Effect of a Novel GLP-1 Analogue Ecnoglutide on the Pharmacokinetics of Rosuvastatin and Digoxin in Healthy Participants.
This Phase 1 open-label crossover study evaluated the effects of ecnoglutide on the pharmacokinetics of rosuvastatin and digoxin in 28 healthy adults.
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