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542 articles

July 202624

Clinical ResearchGeriatricsOpen access

Effect of probiotics on humoral responses to COVID-19 vaccination in older adults: a randomized, placebo-controlled trial (PIRATES-COV study).

This randomized controlled trial evaluated the effect of probiotics on immune responses to COVID-19 vaccination in older adults (ages 65-89) in Quebec, Canada.

Gut MicrobesJul 28, 2026Read summary
Clinical ResearchInternal Medicine (General)

Assessment and CommuniCation ExcelLEnce foR sAfe paTient outcomEs (ACCELERATE): A stepped-wedge cluster randomised trial evaluating the effectiveness of a nurse-led assessment and handover communication intervention on patient adverse events.

The ACCELERATE trial, a stepped-wedge cluster randomised trial conducted over 12 months in three metropolitan hospitals, evaluated a nurse-led assessment and communication intervention aimed at reducing patient adverse…

Int J Nurs StudJul 28, 2026Read summary
Clinical ResearchGeriatrics

Mediterranean diet adherence modulates the plasma antioxidant response to long-term extra-virgin olive oil consumption in older adults.

This randomized controlled trial evaluated the impact of long-term consumption of extra-virgin olive oil (EVOO) on plasma total antioxidant capacity (TEAC) in 34 older adults at high cardiovascular risk.

Clin Nutr ESPENJul 28, 2026Read summary
Clinical ResearchGeriatrics

A self-determination theory-based cognitive prosthetic to improve medication adherence in African American older adults with diabetes.

This randomized controlled trial evaluated the efficacy of MediTeddi, a cognitive prosthetic, in improving medication adherence among African American older adults with poorly controlled type 2 diabetes.

Exp GerontolJul 27, 2026Read summary
Clinical ResearchGeriatrics

Immersive virtual reality cognitive training in older adults with mild cognitive impairment: Feasibility results from a randomized controlled trial.

This single-centre randomized controlled feasibility trial evaluated a 6-week immersive virtual reality (VR) cognitive training program in adults aged 65 years or older with mild cognitive impairment, compared with…

J Psychosom ResJul 27, 2026Read summary
Clinical ResearchGeriatrics

Effect of Virtual Reality-Based Cognitive-Motor Training for Community-Dwelling Older Adults With Mild Cognitive Impairment: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed virtual reality (VR)-based cognitive-motor training in community-dwelling older adults with mild cognitive impairment.

J Clin NursJul 27, 2026Read summary
Clinical ResearchGeriatrics

Age-related differences in motor unit behaviours and maximal strength: A systematic review and meta-analysis.

This systematic review and meta-analysis examined age-related differences in motor unit behaviors and their impact on maximal strength in older versus younger adults.

Neurobiol AgingJul 25, 2026Read summary
Clinical ResearchGeriatrics

Effectiveness of Self-Administered Dual-Task Training in Improving Balance and Reducing Falls Among Older Adults: A Multicenter Randomized Control Trial.

This multicenter randomized controlled trial compared self-administered dual-task training with self-administered single-task training in 216 community-dwelling adults aged 65 years or older who had fallen at least once…

J Phys Act HealthJul 25, 2026Read summary
Clinical ResearchGeriatrics

Effect of Physical Activity Intervention on Blood Pressure in Socioeconomically Disadvantaged Older Adults: A Cluster Randomized Trial.

This cluster-randomized trial examined whether a physical activity intervention affected blood pressure in socioeconomically disadvantaged older adults in eight villages in Sichuan, China.

J Phys Act HealthJul 25, 2026Read summary
Clinical ResearchGeriatrics

Changes in the oral microbiota among dentate, edentate, and complete denture-wearing older adults: A systematic review and meta-analysis.

This systematic review and meta-analysis examined the oral microbiota differences among dentate, edentate, and complete denture-wearing older adults (≥65 years).

J DentJul 24, 2026Read summary
Clinical ResearchNeurology

Association between pulse pressure and markers of cognitive function: a systematic review and meta-analysis.

This systematic review and meta-analysis examined the relationship between pulse pressure (PP) and cognitive function across 43 studies.

J HypertensJul 24, 2026Read summary
Clinical ResearchGeriatrics

Muscle mechanical and architectural adaptations in response to different endurance training modalities in older adults.

This randomized controlled trial investigated the effects of different cycling endurance training modalities on muscle mechanical and architectural characteristics in 50 older adults (ages 59-79).

Exp GerontolJul 24, 2026Read summary
Clinical ResearchOrthopedic Surgery

Artificial intelligence in the evaluation and treatment of osteoporotic and fragility fractures: A systematic review.

This PRISMA-compliant systematic review examined original studies of artificial intelligence, machine learning, and deep learning for evaluating and managing osteoporotic and fragility fractures in adults.

InjuryJul 24, 2026Read summary
Clinical ResearchGeriatrics

Beyond multidimensionality: a systematic review of recurrent frailty archetypes in community-dwelling older adults.

This systematic review examined recurrent frailty archetypes in community-dwelling older adults by analyzing 14 reports from 12 datasets across eight countries.

Arch Gerontol GeriatrJul 23, 2026Read summary
Clinical ResearchInternal Medicine (General)

Effects of nutritional therapy on morphofunctional outcomes in critically ill patients: A systematic narrative synthesis.

This systematic review examined the effects of nutritional therapy on morphofunctional outcomes in critically ill adult ICU patients.

Clin Nutr ESPENJul 23, 2026Read summary
Clinical ResearchNeurologyOpen access

Interstitial fluid rejuvenation through young-donor plasma exchange in cognitively impaired patients: a pilot safety and feasibility study.

This pilot safety and feasibility study evaluated the effects of young-donor plasma exchange in 12 cognitively impaired patients with mild cognitive impairment and Alzheimer's disease biomarkers.

GeroscienceJul 23, 2026Read summary
Clinical ResearchGeriatrics

Effects of free-weight resistance training based on hexagonal barbell deadlift in older women: A 24-week randomized controlled trial.

This randomized controlled trial evaluated the impact of a 24-week hexagonal barbell deadlift (HBDL) resistance training program on body composition and functional performance in 32 older women (average age 67.6 years).

Exp GerontolJul 22, 2026Read summary
Clinical ResearchGeriatrics

Comparing the effects of different exercises on falls in older adults: A network meta-analysis of randomized controlled trials.

This network meta-analysis evaluated the effectiveness of various exercise interventions on fall-related outcomes in 16,240 older adults.

Int J Nurs StudJul 22, 2026Read summary
Clinical ResearchNeurologyOpen access

Dyadic Capability in Stroke Survivors and Their Caregivers: A Systematic Review and Integrated Concept Analysis.

This systematic review and integrated concept analysis examined capability and related constructs in stroke survivors and their caregivers, with the aim of clarifying capability at the dyad level.

J Cardiovasc NursJul 22, 2026Read summary
Clinical ResearchInternal Medicine (General)

Herb-drug interactions with clinical impact: A systematic review of global clinical evidence on medicinal plants widely used in Ecuador.

This systematic review analyzed clinical evidence on herb-drug interactions involving medicinal plants commonly used in Ecuador.

J EthnopharmacolJul 21, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Comparative efficacy of percutaneous vertebroplasty combined with minimally invasive pedicle screw fixation versus percutaneous vertebroplasty alone in the treatment of elderly osteoporotic vertebral compression fractures.

This randomized controlled trial evaluated the efficacy of percutaneous vertebroplasty (PVP) combined with minimally invasive pedicle screw fixation versus PVP alone in 94 elderly patients with osteoporotic vertebral…

Libyan J MedJul 21, 2026Read summary
Clinical ResearchGeriatrics

Comparative effects of 12-week resistance training on unstable and stable surfaces on muscle stiffness, muscle co-activation, and balance in older patients with knee osteoarthritis.

This randomized controlled trial evaluated the effects of unstable resistance training (URT) versus stable resistance training (SRT) on muscle stiffness, co-activation, and balance in older adults with knee…

Gait PostureJul 21, 2026Read summary
Clinical ResearchAnesthesiology

Effects of permissive hypercapnia on intraoperative cerebral oxygenation and early postoperative cognitive function in older patients with fragile brain function during the non-acute phase undergoing laparoscopic colorectal surgery: A randomized controlled trial.

This randomized controlled trial investigated the effects of permissive hypercapnia (PHC) on cerebral oxygenation and cognitive function in 76 older patients with fragile brain function undergoing laparoscopic…

Exp GerontolJul 21, 2026Read summary
Clinical ResearchInternal Medicine (General)

The effect of foot positioning on tissue oxygenation in diabetic foot ulcers.

This randomized controlled trial assessed the impact of foot positioning on tissue oxygenation in 60 hospitalized patients with diabetic foot ulcers.

Diabetes Res Clin PractJul 21, 2026Read summary

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