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412 articles
May 202624
Food-derived components as natural skin-whitening strategies: Classification, mechanisms, application forms and prospects.
This systematic review examines food-derived components for skin whitening, focusing on their mechanisms and applications. It identifies eight major categories, including polyphenols and alkaloids, which inhibit…
Large-scale meta-analysis of infection risk with JAK-STAT inhibitors in 29,000 patients.
This large-scale meta-analysis evaluated the infection risk associated with JAK-STAT inhibitors in over 29,000 patients with immune-mediated inflammatory diseases.
Bowenoid Malignant Onychopapilloma.
A 52-year-old man presented with progressive longitudinal erythronychia of the thumbnail, characterized by increasing width, darkening, and distal keratotic changes.
Early intervention with secukinumab prevents epigenetic scar development in new-onset psoriasis: STEPIn mechanistic substudy results.
This randomized controlled trial investigated the effects of early secukinumab intervention on psoriatic skin lesions in new-onset patients.
Pregnancy Associated Atypical Onychopapilloma: A Novel Presentation of an Emerging Entity in Dermatopathology.
A 37-year-old woman presented with a red longitudinal band on her left thumbnail that developed during her first trimester of pregnancy.
Durability of response to icotrokinra for high-impact site psoriasis: 1-year ICONIC-TOTAL findings.
The ICONIC-TOTAL study, a multicenter randomized controlled trial, evaluated the efficacy and safety of icotrokinra in 311 participants with high-impact site plaque psoriasis over one year.
Sustained on/off-treatment disease control with abrocitinib for moderate-to-severe atopic dermatitis.
This phase III randomized controlled trial evaluated the sustained off-treatment disease control in patients with moderate-to-severe atopic dermatitis after 12 weeks of abrocitinib 200 mg.
Discoid Lupus Erythematosus in Genital Skin: A Case Report and Review of the Literature.
A 60-year-old female with a history of systemic sclerosis presented with erythematous, keratotic plaques in the inguinal creases and medial buttocks, accompanied by pruritus and pain when sitting.
A Crateriform Facial Nodule in a Man With Pulmonary Tuberculosis.
A man with pulmonary tuberculosis presented with a crateriform facial nodule. Upon investigation, the lesion was identified as cutaneous cryptococcosis, a rare manifestation typically resulting from hematogenous spread.
Skin biopsy PCR enables rapid diagnosis of tattoo-associated staphylococcal toxic shock syndrome.
A 29-year-old man presented with fever, diarrhea, hypotension, and purpuric lesions on a calf tattoo done three days prior. Laboratory tests indicated systemic inflammation and acute kidney injury.
Desmoplastic Trichilemmoma Mimicking Basal Cell Carcinoma: Two New Cases, Systematic Review of 92 Cases and Dual Staining Diagnostic Approach.
Two cases of desmoplastic trichilemmoma (DTM) were presented, both mimicking basal cell carcinoma (BCC) due to overlapping features.
Postsurgical pemphigus vulgaris following thyroidectomy: a case report and review of the literature.
A 49-year-old woman developed postsurgical pemphigus vulgaris at the site of a previous thyroidectomy scar. This autoimmune blistering disorder, although rare, can arise from surgical trauma and may extend beyond the…
Scabies Cases in Children are Still on the Rise After the COVID-19 Pandemic.
As a significant increase in the incidence of scabies in adults has been described since 2020, a cross-sectional, single-center, retrospective study was conducted in patients younger than 18 years presenting to the…
Refractory Dermatomyositis Treated With Anifrolumab: Clinical Response and Dynamics of Type-I Interferon Signature.
A patient with refractory dermatomyositis (DM) was treated with anifrolumab, a monoclonal antibody targeting the type-I interferon receptor. The treatment resulted in an almost complete cutaneous response.
Acute generalized exanthematous pustulosis sine pustules.
The report describes AGEP presenting without clinically evident pustules, an atypical presentation that can complicate diagnosis when medication exposure is unclear or several drugs have been started close together.
Systematic review and network meta-analysis of biologics and small molecules for scalp psoriasis.
This systematic review and network meta-analysis compared short-term efficacy, safety and tolerability of biologics and small molecules for scalp psoriasis, using randomized controlled trials.
Treatment of androgenetic alopecia in transgender people receiving testosterone therapy with sublingual minoxidil: A randomized, double-blind, placebo-controlled clinical trial.
This randomized, double-blind, placebo-controlled trial evaluated the efficacy and safety of sublingual minoxidil in treating mild androgenetic alopecia in transgender individuals undergoing testosterone therapy.
The Pre-DIT Technique: A Fascicle-Specific Dual-Plane Approach for Correcting and Preventing Paradoxical Masseteric Bulging After BoNT-A Injection.
Patients treated with masseter botulinum toxin type A developed paradoxical masseteric bulging, typically within the first week after injection.
Management of skin metastases of ovarian cancer: a novel therapeutic approach.
A woman with extensive skin metastases from high-grade serous ovarian carcinoma on her thigh was treated with a novel combination therapy.
Case Series of Ocular Oncocytoma of the Caruncle, Conjunctiva, and Eyelid.
Three cases of periocular oncocytomas were presented, characterized by benign proliferations of oncocytic cells. Histological examination revealed dermal proliferations of eosinophilic cells with granular cytoplasm.
PRAME Immunostaining in Acral Melanocytic Proliferations: A Meta-Analysis.
This meta-analysis evaluated the diagnostic utility of PRAME immunohistochemistry in acral melanocytic proliferations, analyzing 930 lesions from 13 studies.
Reduced-Dose Total Skin Electron Beam Radiation Therapy in Mycosis Fungoides and Sézary Syndrome: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the safety and efficacy of reduced-dose total skin electron beam therapy (TSEBT) in patients with mycosis fungoides and Sézary syndrome.
Beyond efficacy: pulse duration is crucial for adverse events in pulsed dye laser therapy for rosacea.
This randomized controlled trial evaluated the efficacy and tolerability of 6 ms versus 10 ms pulsed dye laser (PDL) treatments in 80 patients with erythematotelangiectatic rosacea.
Rare Presentation of TEN-Like Subacute Cutaneous Lupus Erythematosus Occurring in the Setting of Donepezil Exposure and COVID-19 Infection: A Diagnostic Challenge.
A 65-year-old man developed a widespread, photodistributed erythematous eruption within 24 hours of starting donepezil for Parkinsonism-associated aphasia.
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