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937 articles

September 202624

Clinical ResearchOncology (Medical)

First-line fecal microbiota transplantation for the management of immune checkpoint inhibitor-mediated diarrhea and colitis.

This preliminary clinical trial evaluated first-line fecal microbiota transplantation (FMT) for immune checkpoint inhibitor-mediated diarrhea and colitis (IMDC), using multi-omics profiling.

Cell Rep MedSep 14, 2026Read summary
Clinical ResearchGastroenterology

A 7-mm Covered TIPS Reduces Hepatic Encephalopathy Without Increasing Rebleeding in Cirrhotic Patients With Small Liver: A Randomized Study.

This multicenter randomized controlled trial evaluated the efficacy of 7-mm covered transjugular intrahepatic portosystemic shunts (TIPS) compared to 8-mm stents in cirrhotic patients with small livers.

Liver IntSep 12, 2026Read summary
Clinical ResearchGastroenterology

Early Analgesia for the Management of Acute Pancreatitis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

This systematic review and meta-analysis evaluated the efficacy and safety of early analgesic interventions, specifically comparing NSAIDs to opioids, in adults with acute pancreatitis (AP).

PancreasSep 12, 2026Read summary
Clinical ResearchGastroenterology

Efficacy and Safety of Pancreatoscopy-Guided Laser Lithotripsy Versus Electrohydraulic Lithotripsy in Managing Pancreatic Duct Stone: A System Review and Meta-Analysis.

This meta-analysis compared the efficacy and safety of pancreatoscopy-guided laser lithotripsy (LL) and electrohydraulic lithotripsy (EHL) in treating refractory pancreatic duct stones in 326 patients.

PancreasSep 12, 2026Read summary
Clinical ResearchGastroenterology

Protein sorting and proteostasis mechanisms in CFTR-related exocrine pancreas dysfunction: A systematic narrative review.

This systematic narrative review examines the role of protein sorting mechanisms in CFTR-related exocrine pancreatic dysfunction.

Channels (Austin)Sep 12, 2026Read summary
Clinical ResearchGeneral SurgeryOpen access

Comparative effectiveness and safety of robotic versus laparoscopic liver resection for benign liver diseases: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the effectiveness and safety of robotic liver resection (RLR) versus laparoscopic liver resection (LLR) for benign liver diseases, analyzing data from nine…

BMC GastroenterolSep 12, 2026Read summary
Case ReportMedical Genetics

Identification of a new, likely pathogenic, heterozygous ABCB4 variant causing low phospholipid-associated cholelithiasis.

A late adolescent boy presented with recurrent biliary symptoms after cholecystectomy, alongside elevated cholestatic liver enzymes and a family history of hepatobiliary disease.

BMJ Case RepSep 11, 2026Read case
Clinical ResearchGastroenterologyOpen access

Long-term outcomes in recurrent diverticulitis: a systematic review of treatment strategies and recurrence rates.

This systematic review evaluated long-term outcomes of treatment strategies for recurrent diverticulitis in 446 patients. It found recurrence rates ranging from 5.6% to 21.1% over follow-up periods of 17 to 190 months.

Int J Colorectal DisSep 11, 2026Read summary
Case ReportOncology (Medical)

Primary Hepatic Lymphoma with Hepatocellular Carcinoma: A Case Report.

A patient with hepatocellular carcinoma (HCC) presented with atypical imaging findings that led to the discovery of primary hepatic lymphoma (PHL).

J Vis ExpSep 11, 2026Read case
Case ReportGastroenterologyOpen access

Endoscopic ultrasound-guided left gastric vein embolization for esophageal and gastric varices in liver cirrhosis: A case report.

A 47-year-old man with decompensated cirrhosis presented with hematemesis and melena. Imaging revealed portal hypertension and gastroesophageal varices.

Medicine (Baltimore)Sep 11, 2026Read case
Clinical ResearchGastroenterologyOpen access

Cost-effectiveness analysis of omeprazole for preventing esophageal stricture in patients with Zargar grade 2b and 3a corrosive esophageal injuries: A trial-based economic evaluation.

This randomized controlled trial evaluated the cost-effectiveness of omeprazole combined with standard treatment versus standard treatment alone in adults with Zargar grade 2b and 3a corrosive esophageal injuries.

Medicine (Baltimore)Sep 11, 2026Read summary
Case ReportGastroenterologyOpen access

Long-term outcome of percutaneous transhepatic venous embolization for ectopic peristomal variceal bleeding: A case report.

A patient with an ileal neobladder experienced recurrent hematuria due to ectopic peristomal varices linked to portal hypertension.

Medicine (Baltimore)Sep 11, 2026Read case
Case ReportGastroenterologyOpen access

Acute bowel ischemia in the absence of radiological findings: A case for endoscopy.

A 73-year-old man presented in septic shock with elevated inflammatory markers and inconclusive clinical and radiological findings for bowel ischemia. Endoscopy was performed, revealing transmural bowel ischemia.

Medicine (Baltimore)Sep 11, 2026Read case
Clinical ResearchGastroenterologyOpen access

Randomized controlled trial comparing 7-day fexuprazan-based and 14-day rabeprazole-based triple therapies for Helicobacter pylori eradication.

This randomized controlled trial evaluated the efficacy and safety of a 7-day fexuprazan-based triple therapy versus a 14-day rabeprazole-based regimen for Helicobacter pylori eradication in Korean patients.

Medicine (Baltimore)Sep 11, 2026Read summary
Clinical ResearchCardiologyOpen access

Multitarget Pharmacological Mechanisms and Safety Profiles of Six Ethnobotanically Prioritized Indonesian Medicinal Plants for Cardiometabolic Disorders: A Systematic Review.

This systematic review evaluated the pharmacological effects and safety of six Indonesian medicinal plants for cardiometabolic disorders.

Drug Des Devel TherSep 11, 2026Read summary
Clinical ResearchGeneral Surgery

Normothermic machine perfusion versus static cold storage for liver transplantation: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the effectiveness of normothermic machine perfusion (NMP) versus static cold storage (SCS) in liver transplantation, involving 630 recipients across five studies.

Acta Cir BrasSep 11, 2026Read summary
Case ReportMedical Genetics

Clinical and genetic analysis of a family with 16p11.2 microduplication syndrome and variable multisystem manifestations.

A multigenerational family was studied for 16p11.2 microduplication syndrome, with the proband presenting symptoms including limb muscle pain, exercise intolerance, and chronic gastrointestinal issues.

GeneSep 11, 2026Read case
Clinical ResearchOncology (Medical)

Oncological impact of adjuvant chemotherapy after rectal cancer excision in the era of FOLFIRINOX-based TNT: A pooled post-hoc analysis of GRECCAR4-PRODIGE23.

This multicenter randomized controlled trial analyzed the impact of adjuvant chemotherapy (AC) on oncological outcomes in patients with locally advanced rectal cancer (LARC) following total neoadjuvant therapy (TNT) or…

Eur J CancerSep 11, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Redo Heller myotomy vs. POEM after failed Heller myotomy: a systematic review and meta-analysis.

This systematic review and meta-analysis compared redo Heller myotomy and peroral endoscopic myotomy (POEM) in 631 patients with recurrent symptoms after laparoscopic Heller myotomy.

Surg EndoscSep 11, 2026Read summary
Clinical ResearchGastroenterology

Long-term outcomes of top-down therapy versus a conventional step-up strategy in adults newly diagnosed with Crohn's disease: 5-year follow-up of the PROFILE trial.

This multicentre, open-label randomised trial follow-up compared early top-down infliximab plus an immunomodulator with protocolised step-up treatment in adults aged 16–80 years newly diagnosed with Crohn’s disease.

Lancet Gastroenterol HepatolSep 11, 2026Read summary
Clinical ResearchGastroenterology

Clinical Trial: Randomised Placebo-Controlled Trial of Methylcellulose and Psyllium Gels on Inulin-Induced Colonic Gas.

This three-way randomised crossover trial compared methylcellulose, psyllium and maltodextrin placebo, each given with inulin, in 22 healthy volunteers.

Aliment Pharmacol TherSep 11, 2026Read summary
Clinical ResearchGastroenterology

Optimization strategies for care‑giving behaviors of family caregivers for patients with enterostomy: An evidence summary.

This systematic review summarizes evidence on optimizing caregiving behaviors for family caregivers of patients with enterostomy.

PLoS OneSep 10, 2026Read summary
Clinical ResearchMedical Genetics

Genetic basis of pancreatic steatosis: a systematic review of comparison between African and non-African populations.

This systematic review examined genetic factors associated with pancreatic steatosis in African versus non-African populations, analyzing data from over 120,000 participants.

Physiol GenomicsSep 10, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Comparing long-term weight loss and complications in endoscopic sleeve gastroplasty and laparoscopic sleeve gastrectomy: a systematic review and meta-analysis.

This systematic review and meta-analysis compared long-term outcomes of endoscopic sleeve gastroplasty (ESG) and laparoscopic sleeve gastrectomy (LSG) in 7442 patients.

Surg EndoscSep 10, 2026Read summary

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